Lindekleiv H M, Jacobsen E A, Kloster R, Sandell T, Isaksen J G, Romner B, Ingebrigtsen T, Bajic R
Department of Radiology, University Hospital of North Norway, Tromsø, Norway.
Acta Radiol. 2009 Jun;50(5):555-61. doi: 10.1080/02841850902915740.
Studies indicate a relationship between hospital caseload and health outcomes after both surgical and endovascular repair of intracranial aneurysms.
To evaluate outcomes after introduction of endovascular embolization for intracranial aneurysms in a low-volume regional university hospital.
Retrospective study of 243 consecutive patients treated for 284 intracranial aneurysms with endovascular embolization or surgical clipping from 2000 to 2006 at the University Hospital of North Norway. Postoperative complications were registered. The Glasgow Outcome Scale (GOS) was used for assessment of outcome.
The mean annual number of procedures was 39 (microsurgery 23, embolization 16). Seventy-four percent of patients with ruptured aneurysms and all patients with unruptured aneurysms had a favorable outcome (GOS 4 or 5) at 1 year follow-up. Patients with subarachnoid hemorrhage were more likely to experience postoperative complications than patients treated for unruptured aneurysms (42% versus 8% of the patients, P<0.01). The immediate incomplete occlusion rate (Raymond II-III) in the initial embolization procedure was 29%. Ten endovascularly treated patients and one surgically treated patient required retreatments due to residual aneurysm or neck remnants.
The present study indicates that acceptable outcome from aneurysm treatment, both endovascular and microsurgical, is possible in a low-volume institution.
研究表明,颅内动脉瘤的手术和血管内修复术后,医院病例数量与健康结局之间存在关联。
评估在一家病例数量较少的地区性大学医院引入颅内动脉瘤血管内栓塞术后的结局。
对2000年至2006年在挪威北部大学医院接受血管内栓塞或手术夹闭治疗284例颅内动脉瘤的243例连续患者进行回顾性研究。记录术后并发症。采用格拉斯哥预后量表(GOS)评估结局。
平均每年手术例数为39例(显微手术23例,栓塞术16例)。74%的动脉瘤破裂患者和所有动脉瘤未破裂患者在1年随访时预后良好(GOS 4或5)。蛛网膜下腔出血患者比动脉瘤未破裂患者更易发生术后并发症(分别为42%和8%的患者,P<0.01)。初始栓塞术时的即刻不完全闭塞率(雷蒙德II - III级)为29%。10例接受血管内治疗的患者和1例接受手术治疗的患者因残留动脉瘤或颈部残留需要再次治疗。
本研究表明,在病例数量较少的机构中,无论是血管内治疗还是显微手术治疗动脉瘤,都可能获得可接受的结局。