Mordyk A V, Briukhanova N S, Kazakov A V
Probl Tuberk Bolezn Legk. 2009(3):38-42.
The impact of disease and treatment on the mental status of patients with infiltrative pulmonary tuberculosis was studied. The study included 39 patients, chemotherapy in whom was complicated by the development of adverse reactions and 33 patients who had no adverse reactions. In new cases of tuberculosis, anxiety and personality disorders before chemotherapy were ascertained to be a response to first diagnosed tuberculosis and forced long-term in the inpatient setting. The development of adverse reactions caused by antituberculous agents during therapy was accompanied by impairments in psychological adaptation processes, the preservation and worsening of anxiety and personality disorders, which determines it necessary to include additional drug and psychotherapeutic correction methods into a package of therapeutic measures in tuberculosis.
研究了疾病及治疗对浸润性肺结核患者精神状态的影响。该研究纳入了39例化疗出现不良反应的患者以及33例未出现不良反应的患者。在新发肺结核病例中，化疗前的焦虑和人格障碍被确定为对首次诊断出肺结核以及在住院环境中被迫长期治疗的一种反应。治疗期间抗结核药物引起的不良反应的出现伴随着心理适应过程的受损、焦虑和人格障碍的持续及加重，这决定了有必要在肺结核治疗措施中加入额外的药物和心理治疗矫正方法。
