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颈部情况复杂的腹主动脉瘤:开放手术与使用标准及开窗支架型人工血管进行血管腔内修复的效果对比

The AAA with a challenging neck: outcome of open versus endovascular repair with standard and fenestrated stent-grafts.

作者信息

Chisci Emiliano, Kristmundsson Thorarinn, de Donato Gianmarco, Resch Timothy, Setacci Francesco, Sonesson Björn, Setacci Carlo, Malina Martin

机构信息

Vascular and Endovascular Surgery Unit, University of Siena, Italy.

出版信息

J Endovasc Ther. 2009 Apr;16(2):137-46. doi: 10.1583/08-2531.1.

Abstract

PURPOSE

To compare the outcome of endovascular aneurysm repair (EVAR) versus conventional open repair (OR) in patients with a short, angulated or otherwise challenging proximal neck.

METHODS

The definition of a challenging proximal neck was based on diameter (>or=28 mm), length (<or=15 mm), angulation (>or=60 degrees ), shape (reverse tapered or bulging), and thrombus lining (>50%). Between January 2005 and December 2007, 187 consecutive patients (159 men; mean age 73 years, range 48-92) operated for asymptomatic abdominal aortic aneurysm (AAA) were identified as having challenging proximal neck morphology. Of these, 61 patients were treated with OR at center I (group A), 71 with standard EVAR (group B; 45 center I, 29 center II) and 52 with fenestrated EVAR (group C) at center II. Clinical examination and computed tomography were performed at 1 month and yearly thereafter.

RESULTS

There was no statistically significant difference between groups A, B, and C regarding primary technical success rate, 30-day mortality, or late AAA-related mortality. The mean length of follow-up was 19.5 months (range 0-40). Freedom from reintervention at 3 years was 91.8%, 79.7%, and 82.7% for groups A, B, and C, respectively (p = 0.042). The only statistically significant difference between standard and fenestrated EVAR was a higher incidence of late sac expansion [9 (12.2%) versus 1 (1.9%), p = 0.036] in the standard stent-graft group. Reinterventions were more frequent after EVAR (p = NS), but open reinterventions were more common after OR. Reinterventions after EVAR were related to the presence of an angulated (p = 0.039) or short neck (p = 0.024).

CONCLUSION

The results of EVAR and OR were similar for AAAs with a challenging proximal neck. Endovascular reinterventions were more frequent after EVAR, particularly in patients with an angulated or short neck. Open reinterventions were more common after OR. More patients and long-term data are needed to confirm these findings.

摘要

目的

比较血管内动脉瘤修复术(EVAR)与传统开放修复术(OR)在近端瘤颈短、成角或存在其他挑战性情况的患者中的治疗效果。

方法

具有挑战性的近端瘤颈的定义基于直径(≥28mm)、长度(≤15mm)、成角(≥60度)、形状(反向锥形或膨出)以及血栓内膜(>50%)。在2005年1月至2007年12月期间,187例连续接受无症状腹主动脉瘤(AAA)手术的患者(159例男性;平均年龄73岁,范围48 - 92岁)被确定为具有挑战性的近端瘤颈形态。其中,61例患者在中心I接受OR治疗(A组),71例接受标准EVAR治疗(B组;45例在中心I,29例在中心II),52例在中心II接受开窗EVAR治疗(C组)。术后1个月及之后每年进行临床检查和计算机断层扫描。

结果

A、B、C三组在主要技术成功率、30天死亡率或晚期AAA相关死亡率方面无统计学显著差异。平均随访时间为19.5个月(范围0 - 40个月)。A、B、C三组3年无再次干预的比例分别为91.8%、79.7%和82.7%(p = 0.042)。标准EVAR与开窗EVAR之间唯一具有统计学显著差异的是标准支架移植物组晚期瘤腔扩张发生率更高[9例(12.2%)对1例(1.9%),p = 0.036]。EVAR术后再次干预更频繁(p = 无统计学意义),但OR术后开放再次干预更常见。EVAR术后再次干预与成角(p = 0.039)或短瘤颈(p = 0.024)有关。

结论

对于近端瘤颈具有挑战性的AAA,EVAR和OR的结果相似。EVAR术后血管内再次干预更频繁,尤其是在瘤颈成角或短的患者中。OR术后开放再次干预更常见。需要更多患者和长期数据来证实这些发现。

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