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血管腔内主动脉修复术给腹主动脉瘤的治疗策略带来了什么?

What Did Endovascular Aortic Repair Bring for the Treatment Strategy of Abdominal Aortic Aneurysm?

作者信息

Midorikawa Hirofumi, Takano Takashi, Ueno Kyohei, Takinami Gaku, Kageyama Rie, Seki Haruna, Kanno Megumu, Satou Kouichi

机构信息

Department of Cardiovascular Surgery, Southern TOHOKU General Hospital, Koriyama, Fukushima, Japan.

Department of Cardiovascular Surgery, Sukagawa Hospital, Sukagawa, Fukushima, Japan.

出版信息

Ann Vasc Dis. 2018 Dec 25;11(4):484-489. doi: 10.3400/avd.oa.18-00099.

Abstract

: We examined the effects of the introduction of endovascular aortic repair (EVAR) on treatment for abdominal aortic aneurysms (AAAs). : We compared patients in the following three periods: period I (January 2002-December 2006, 105 patients), period II (January 2007-December 2011, 242 patients, duration of 5 years after the introduction of EVAR), and period III (January 2012-December 2016, 237 patients, duration of 5 years after period II). We used the American Society of Anesthesiologists (ASA) classification for risk assessment. : In the Open repair (OR) group, the incidences of ASA class 2 increased and classes 3 and 4 decreased significantly in periods II and III compared with period I. In all periods, there were no in-hospital deaths. Suprarenal aortic cross-clamping was required in 18 patients (19.1%) in period III and 5 patients (6.3) in period I, and the difference was significant (P<0.05). In the EVAR group, no differences in age, sex, or ASA classification class were observed between periods II and III. In period II, one patient died due to aneurysm rupture during surgery. Significant differences were observed when comparing both groups in periods II and III: patients in the EVAR group were older (P<0.01) and the OR group had a higher proportion of ASA class 2 patients and the EVAR group had a higher proportion of ASA class 3 or 4 patients (P<0.01). Among all AAA surgeries, rupture occurred in 25 patients (23.8%) in period I, 18 patients (7.4) in period II, and 16 patients (6.8) in period III. The number of ruptures was significantly lower in periods II and III than in period I (P<0.01). : The findings of this study suggest that EVAR should be indicated for high-risk patients and had the good outcome of AAA treatment. (This is a translation of Jpn J Vasc Surg 2018; 27: 27-32.).

摘要

我们研究了血管内主动脉修复术(EVAR)的引入对腹主动脉瘤(AAA)治疗的影响。我们比较了以下三个时期的患者:第一期(2002年1月 - 2006年12月,105例患者)、第二期(2007年1月 - 2011年12月,242例患者,EVAR引入后5年)和第三期(2012年1月 - 2016年12月,237例患者,第二期后5年)。我们采用美国麻醉医师协会(ASA)分级进行风险评估。在开放修复(OR)组中,与第一期相比,第二期和第三期ASA 2级的发生率增加,3级和4级的发生率显著降低。在所有时期,均无院内死亡病例。第三期有18例患者(19.1%)需要进行肾上主动脉交叉钳夹,第一期有5例患者(6.3%)需要进行,差异有统计学意义(P<0.05)。在EVAR组中,第二期和第三期在年龄、性别或ASA分级方面未观察到差异。在第二期,有1例患者在手术期间因动脉瘤破裂死亡。在比较第二期和第三期的两组时观察到显著差异:EVAR组患者年龄较大(P<0.01),OR组中ASA 2级患者比例较高,EVAR组中ASA 3级或4级患者比例较高(P<0.01)。在所有AAA手术中,第一期有25例患者(23.8%)发生破裂,第二期有18例患者(7.4%),第三期有16例患者(6.8%)。第二期和第三期的破裂例数显著低于第一期(P<0.01)。本研究结果表明,EVAR适用于高危患者,并且对AAA治疗有良好的效果。(本文翻译自《日本血管外科学杂志》2018年;27: 27 - 32.)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6611/6326053/e39a398d00c2/avd-11-4-oa.18-00099-figure01.jpg

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