Dores Robert M
Department of Biological Sciences, University of Denver, Denver, Colorado 80210, USA.
Ann N Y Acad Sci. 2009 Apr;1163:93-100. doi: 10.1111/j.1749-6632.2009.04434.x.
In 1977 Dr. Robert Schwyzer wrote the review ACTH: A Short Introductory Review, which provided a reference point for current structure/function studies on the interactions between adrenocorticotropic hormone and alpha-melanocyte-stimulating hormone and the melanocortin receptors. This mini review will evaluate how the predictions made in the 1977 review have held up and also propose a mechanism to explain the ligand selectivity properties of the melanocortin receptors.
1977年,罗伯特·施维泽博士撰写了综述《促肾上腺皮质激素:简短的介绍性综述》,该综述为目前关于促肾上腺皮质激素与α-黑素细胞刺激素之间相互作用以及黑皮质素受体的结构/功能研究提供了一个参考点。这篇小型综述将评估1977年综述中的预测是如何得到验证的,并提出一种机制来解释黑皮质素受体的配体选择性特性。