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1
Synergistic effects of inward rectifier (I) and pacemaker (I) currents on the induction of bioengineered cardiac automaticity.
J Cardiovasc Electrophysiol. 2009 Sep;20(9):1048-54. doi: 10.1111/j.1540-8167.2009.01475.x.
2
Mechanistic role of I(f) revealed by induction of ventricular automaticity by somatic gene transfer of gating-engineered pacemaker (HCN) channels.
Circulation. 2007 Apr 10;115(14):1839-50. doi: 10.1161/CIRCULATIONAHA.106.659391. Epub 2007 Mar 26.
3
Overexpression of HCN-encoded pacemaker current silences bioartificial pacemakers.
Heart Rhythm. 2008 Sep;5(9):1310-7. doi: 10.1016/j.hrthm.2008.05.010. Epub 2008 May 15.
6
Recreating an artificial biological pacemaker: insights from a theoretical model.
Heart Rhythm. 2006 Jul;3(7):824-31. doi: 10.1016/j.hrthm.2006.03.012. Epub 2006 Mar 16.
7
Non-equilibrium behavior of HCN channels: insights into the role of HCN channels in native and engineered pacemakers.
Cardiovasc Res. 2005 Aug 1;67(2):263-73. doi: 10.1016/j.cardiores.2005.03.006. Epub 2005 Apr 21.
10
Kir2.1 channels set two levels of resting membrane potential with inward rectification.
Pflugers Arch. 2018 Apr;470(4):599-611. doi: 10.1007/s00424-017-2099-3. Epub 2017 Dec 27.

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4
Gene Therapy Approaches to Biological Pacemakers.
J Cardiovasc Dev Dis. 2018 Oct 19;5(4):50. doi: 10.3390/jcdd5040050.
7
Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review).
Int J Mol Med. 2017 Mar;39(3):519-526. doi: 10.3892/ijmm.2017.2877. Epub 2017 Feb 6.
9
Stem cell-based biological pacemakers from proof of principle to therapy: a review.
Cytotherapy. 2014 Jul;16(7):873-80. doi: 10.1016/j.jcyt.2014.02.014. Epub 2014 May 13.
10
Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells.
J Cardiovasc Transl Res. 2013 Dec;6(6):989-99. doi: 10.1007/s12265-013-9510-z. Epub 2013 Oct 1.

本文引用的文献

1
Overexpression of HCN-encoded pacemaker current silences bioartificial pacemakers.
Heart Rhythm. 2008 Sep;5(9):1310-7. doi: 10.1016/j.hrthm.2008.05.010. Epub 2008 May 15.
2
Structural and functional determinants in the S5-P region of HCN-encoded pacemaker channels revealed by cysteine-scanning substitutions.
Am J Physiol Cell Physiol. 2008 Jan;294(1):C136-44. doi: 10.1152/ajpcell.00340.2007. Epub 2007 Nov 7.
3
HCN-encoded pacemaker channels: from physiology and biophysics to bioengineering.
J Membr Biol. 2006;214(3):115-22. doi: 10.1007/s00232-006-0881-9. Epub 2007 Jun 8.
4
New insights into pacemaker activity: promoting understanding of sick sinus syndrome.
Circulation. 2007 Apr 10;115(14):1921-32. doi: 10.1161/CIRCULATIONAHA.106.616011.
5
Mechanistic role of I(f) revealed by induction of ventricular automaticity by somatic gene transfer of gating-engineered pacemaker (HCN) channels.
Circulation. 2007 Apr 10;115(14):1839-50. doi: 10.1161/CIRCULATIONAHA.106.659391. Epub 2007 Mar 26.
7
Wild-type and mutant HCN channels in a tandem biological-electronic cardiac pacemaker.
Circulation. 2006 Sep 5;114(10):992-9. doi: 10.1161/CIRCULATIONAHA.106.617613. Epub 2006 Aug 21.
8
Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel.
N Engl J Med. 2006 Jan 12;354(2):151-7. doi: 10.1056/NEJMoa052475.
9
Non-equilibrium behavior of HCN channels: insights into the role of HCN channels in native and engineered pacemakers.
Cardiovasc Res. 2005 Aug 1;67(2):263-73. doi: 10.1016/j.cardiores.2005.03.006. Epub 2005 Apr 21.
10
The inward rectifier current (IK1) controls cardiac excitability and is involved in arrhythmogenesis.
Heart Rhythm. 2005 Mar;2(3):316-24. doi: 10.1016/j.hrthm.2004.11.012.

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