Chijiwa H, Mihoki T, Shin B, Sakamoto K, Umeno H, Nakashima T
Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Kurume, Japan.
J Laryngol Otol Suppl. 2009(31):100-3. doi: 10.1017/S0022215109005180.
This study reviewed 24 cases of parapharyngeal space tumour treated at Kurume University Hospital between 1990 and 2007. Histological diagnoses were generally obtained from the excised tumour (22/24). Seventy-seven per cent of the parapharyngeal space tumours were benign and 23 per cent were malignant. Thirty-eight per cent (eight of 22) of these tumours were pleomorphic adenomas and 23 per cent (five of 22) were schwannomas. A transparotidectomy and transcervical approach were used in 88 per cent (15/17) of benign tumours. A mandibular swing approach was used for one malignant tumour. Post-operative complications were identified in 16 of 22 patients. The most common complication, facial nerve paralysis, was identified in eight patients, and seven of these patients demonstrated first bite syndrome. In consideration of the high incidence of post-operative complications, the surgical approach should therefore be carefully selected when treating patients with parapharyngeal space tumours.
本研究回顾了1990年至2007年间在久留米大学医院接受治疗的24例咽旁间隙肿瘤患者。组织学诊断通常来自切除的肿瘤(24例中的22例)。77%的咽旁间隙肿瘤为良性,23%为恶性。这些肿瘤中38%(22例中的8例)为多形性腺瘤,23%(22例中的5例)为神经鞘瘤。88%(17例中的15例)的良性肿瘤采用了透明质酸酶切除术和经颈入路。1例恶性肿瘤采用了下颌骨摆动入路。22例患者中有16例出现术后并发症。最常见的并发症是面神经麻痹,8例患者出现该并发症,其中7例患者表现为初咬综合征。鉴于术后并发症的发生率较高,因此在治疗咽旁间隙肿瘤患者时应谨慎选择手术入路。