Department of Specialist Surgery, ENT Unit, Udine University Hospital, Ple S Maria della Misericordia 15, 33100 Udine, Italy.
Eur Arch Otorhinolaryngol. 2012 Jul;269(7):1723-32. doi: 10.1007/s00405-011-1846-x. Epub 2011 Dec 9.
Eustachian tube (ET) primary tumors and tumor-like lesions are rare diseases presenting with common ear, nose and throat symptoms. Pathology can range from developmental anomalies to high malignant neoplasms. Hence this review aimed at suggesting a classification and outline relevant aspects of ET primary tumors and tumor-like lesions, describing clinical findings, diagnostic management and therapeutic approaches. MEDLINE, CINAHL, OVIDSP, HIGHWIRE, and GOOGLE databases were searched from inception to July 2011 for relevant studies. Further papers were identified by examining the reference lists of all included. Sixty-five papers met the inclusion criteria, enclosing 78 cases. Case reports are increasing in the past few years. Benign lesions and tumor-like lesions of ET have been reported. Moreover, melanomas, carcinomas, and sarcomas can affect the ET as a primary site.
咽鼓管（ET）原发性肿瘤和肿瘤样病变是罕见疾病，表现为常见的耳、鼻和喉症状。病理变化范围从发育异常到高度恶性肿瘤。因此，本综述旨在提出一种分类，并概述 ET 原发性肿瘤和肿瘤样病变的相关方面，描述临床发现、诊断管理和治疗方法。从建库到 2011 年 7 月，我们在 MEDLINE、CINAHL、OVIDSP、HIGHWIRE 和 GOOGLE 数据库中搜索了相关研究。通过检查所有纳入研究的参考文献，进一步确定了其他文献。65 篇论文符合纳入标准，共包括 78 例。近年来，病例报告的数量不断增加。咽鼓管的良性病变和肿瘤样病变已有报道。此外，黑色素瘤、癌和肉瘤也可作为原发性肿瘤影响咽鼓管。
