Exercise and Sport Injury Laboratory, University of Virginia, Charlottesville, VA, USA.
Med Sci Sports Exerc. 2009 Jun;41(6):1175-81. doi: 10.1249/MSS.0b013e3181982557.
To determine whether transcutaneous electrical nerve stimulation (TENS) and focal knee joint cooling will affect the quadriceps central activation ratio (CAR) in patients with tibiofemoral osteoarthritis.
Thirty-three participants with diagnosed tibiofemoral osteoarthritis were randomly allocated to the 45-min TENS treatment (six males and four females, 56 +/- 10.1 yr, 174.11 +/- 10.78 cm, 89.34 +/- 21.3 kg), the 20-min focal knee joint cooling treatment (six males and five females, 58 +/- 8.4 yr, 176.41 +/- 8.29 cm, 83.18 +/- 17.97 kg), or the control group (five males and seven females, 54 +/- 9.9 yr, 166.37 +/- 13.07 cm, 92.14 +/- 25.37 kg). Volitional quadriceps activation, maximal voluntary isometric contraction, and subjective pain measurements were conducted at baseline and at 20, 30, and 45 min. The 20-min focal knee joint cooling intervention consisted of two 1.5-L ice bags to the anterior and posterior aspects of the knee. The TENS group received 45 min of a sensory, biphasic square wave stimulation (150-mus phase duration and 150 pps) from four 2 x 2-inch electrodes positioned around the patella.
: TENS resulted in a significantly higher percent change in CAR scores compared with control at 20 min (6.4 +/- 4.8 vs -3.5 +/- 8, P = 0.006), 30 min (9.7 +/- 10.16 vs -1 +/- 7.9, P = 0.025), and 45 min (11.25 +/- 6.96 vs 0.81 +/- 9.4, P = 0.029). Focal knee joint cooling resulted in significantly higher percent change scores compared with the control group at 20 min (5.75 +/- 7.25 vs -3.5 +/- 8, P = 0.009) and trended to be higher at 45 min (9.06 +/- 9.63 vs 0.81 +/- 9.4, P = 0.098). No significant differences in percent change for CAR were found between the TENS and the focal knee joint cooling group.
Both TENS and focal knee joint cooling increased the quadriceps CAR immediately after application in participants with tibiofemoral osteoarthritis.
确定经皮神经电刺激（TENS）和膝关节焦点冷却是否会影响膝骨关节炎患者的股四头肌中枢激活比（CAR）。
33 名经诊断患有膝骨关节炎的参与者被随机分配至 45 分钟 TENS 治疗组（6 名男性和 4 名女性，56 ± 10.1 岁，174.11 ± 10.78cm，89.34 ± 21.3kg）、20 分钟膝关节焦点冷却治疗组（6 名男性和 5 名女性，58 ± 8.4 岁，176.41 ± 8.29cm，83.18 ± 17.97kg）或对照组（5 名男性和 7 名女性，54 ± 9.9 岁，166.37 ± 13.07cm，92.14 ± 25.37kg）。在基线和 20、30 和 45 分钟时进行自愿性股四头肌激活、最大自主等长收缩和主观疼痛测量。膝关节焦点冷却干预持续 20 分钟，包括两个 1.5 升冰袋置于膝关节的前侧和后侧。TENS 组接受 45 分钟的感觉、双相方波刺激（150 微秒相持续时间和 150pps），由四个 2x2 英寸电极置于髌骨周围。
TENS 在 20 分钟（6.4 ± 4.8 对-3.5 ± 8，P = 0.006）、30 分钟（9.7 ± 10.16 对-1 ± 7.9，P = 0.025）和 45 分钟（11.25 ± 6.96 对 0.81 ± 9.4，P = 0.029）时，CAR 评分的百分比变化明显高于对照组。膝关节焦点冷却在 20 分钟时（5.75 ± 7.25 对-3.5 ± 8，P = 0.009）与对照组相比，CAR 评分的百分比变化明显更高，在 45 分钟时也有较高的趋势（9.06 ± 9.63 对 0.81 ± 9.4，P = 0.098）。TENS 组和膝关节焦点冷却组的 CAR 百分比变化无显著差异。
在膝骨关节炎患者中，TENS 和膝关节焦点冷却均可在应用后立即增加股四头肌 CAR。
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