Kalich R
Forschungsinstitut für Lungenkrankheiten und Tuberkulose, Berlin-Buch.
Pneumologie. 1991 Sep;45(9):725-8.
The frequency of primary drug resistance in patients treated in hospital because of tuberculosis of the lung in 1988 was 1.4% (10 patients), there is a low decrease compared with years before. Also the frequency of acquired drug resistance is with 14.9% lower compared to 1983 (20%). The resistance rate (acquired resistance) to RMP has been nearly the same since 1980, in about 3%. In patients from foreign countries the rate of resistance was higher than in native patients. In 18% resistance was found to one or more drugs at the beginning of the therapy.