Kalich R
Forschungsinstitut für Lungenkrankheiten und Tuberkulose, Berlin-Buch.
Pneumologie. 1991 Sep;45(9):725-8.
The frequency of primary drug resistance in patients treated in hospital because of tuberculosis of the lung in 1988 was 1.4% (10 patients), there is a low decrease compared with years before. Also the frequency of acquired drug resistance is with 14.9% lower compared to 1983 (20%). The resistance rate (acquired resistance) to RMP has been nearly the same since 1980, in about 3%. In patients from foreign countries the rate of resistance was higher than in native patients. In 18% resistance was found to one or more drugs at the beginning of the therapy.
1988年因肺部结核在医院接受治疗的患者中,原发性耐药的发生率为1.4%(10例患者),与之前几年相比有所下降,但降幅较小。此外,获得性耐药的发生率为14.9%,比1983年(20%)有所降低。自1980年以来,对利福平的耐药率(获得性耐药)几乎相同,约为3%。外国患者的耐药率高于本国患者。在18%的患者中,治疗开始时发现对一种或多种药物耐药。