Mahajan M, Agarwal D S, Gadre D J, Singh N P, Gupta H C, Talwar V
Department of Microbiology, University College of Medical Sciences, New Delhi.
J Commun Dis. 1996 Mar;28(1):15-9.
One hundred and fifty six strains of Mycobacterium tuberculosis, isolated from cases of pulmonary tuberculosis were subjected to sensitivity test to detect initial and acquired drug resistance to Streptomycin, isoniazid, Rifampicin, Ethambutol and Pyrazinamide. Initial and acquired drug resistance was observed to one or more drugs in 16% and 24.4% of the patients respectively. Strains resistant to Rifampicin and Ethambutol were resistant to Isoniazid also. Drug resistance was unrelated to age and sex of the patients.
从肺结核病例中分离出156株结核分枝杆菌，对其进行药敏试验，以检测对链霉素、异烟肼、利福平、乙胺丁醇和吡嗪酰胺的初始耐药性和获得性耐药性。分别在16%和24.4%的患者中观察到对一种或多种药物的初始耐药性和获得性耐药性。对利福平和乙胺丁醇耐药的菌株对异烟肼也耐药。耐药性与患者的年龄和性别无关。
