Suppr超能文献

缺血性二尖瓣反流的修复:柔性与刚性瓣环成形环的比较

Repair of ischemic mitral regurgitation: comparison between flexible and rigid annuloplasty rings.

作者信息

Silberman Shuli, Klutstein Marc W, Sabag Tsipora, Oren Avraham, Fink Daniel, Merin Ofer, Bitran Daniel

机构信息

Department of Cardiothoracic Surgery, Shaare Zedek Medical Center, Jerusalem, Israel.

出版信息

Ann Thorac Surg. 2009 Jun;87(6):1721-6; discussion 1726-7. doi: 10.1016/j.athoracsur.2009.03.066.

Abstract

BACKGROUND

The surgical treatment of ischemic mitral regurgitation (MR) usually involves implantation of an annuloplasty ring. We compared results of mitral valve repair using a flexible or a rigid annuloplasty ring in patients with ischemic MR undergoing coronary artery bypass graft surgery.

METHODS

There were 169 patients. A flexible ring was implanted in 117 and a rigid ring in 52. Age and clinical profile, degree of left ventricular dysfunction, and degree of MR (mean 3.2) were similar between groups.

RESULTS

Operative mortality was 9% in each group. Follow-up (58 +/- 30 months for flexible group and 14 +/- 7 months for rigid group) was available for 91%. For the flexible and rigid ring groups, respectively, mean New York Heart Association functional class was 1.9 and 1.6, with 33% and 14% in classes III to IV (p = 0.03); mean MR grade was 1.25 and 0.7 (p = 0.006). There was no difference in left ventricle function or dimensions. At follow-up, 29 patients (34%) in the flexible group had residual MR of moderate degree or greater compared with 6 (15%) in the rigid group (p = 0.03). Mean tricuspid incompetence gradient was 39 and 34 mm Hg (p = nonsignificant); however, the degree of reduction was greater in the rigid group (p = 0.001). Late mortality was observed in 32 patients, all in the flexible group.

CONCLUSIONS

Clinical and hemodynamic results are better with rigid mitral annuloplasty rings compared with flexible rings. That result may be due to ring design, which dictates not only the annular diameter but also annular configuration. Longer follow-up is needed to determine differences in survival.

摘要

背景

缺血性二尖瓣反流(MR)的外科治疗通常涉及植入瓣环成形环。我们比较了在接受冠状动脉搭桥手术的缺血性MR患者中使用柔性或刚性瓣环成形环进行二尖瓣修复的结果。

方法

共有169例患者。117例植入柔性环,52例植入刚性环。两组患者的年龄和临床特征、左心室功能障碍程度以及MR程度(平均3.2)相似。

结果

每组的手术死亡率均为9%。91%的患者获得随访(柔性组为58±30个月,刚性组为14±7个月)。柔性环组和刚性环组的纽约心脏协会功能分级平均分别为1.9和1.6,III至IV级分别为33%和14%(p = 0.03);平均MR分级分别为1.25和o.7(p = 0.006)。左心室功能或尺寸无差异。随访时,柔性环组有29例患者(34%)存在中度或更严重的残余MR,而刚性环组为6例(15%)(p = 0.03)。三尖瓣反流平均压差分别为39和34 mmHg(p = 无显著性差异);然而,刚性环组的降低程度更大(p = 0.001)。32例患者出现晚期死亡,均在柔性环组。

结论

与柔性瓣环成形环相比,刚性瓣环成形环的临床和血流动力学结果更好。这一结果可能归因于瓣环成形环的设计,其不仅决定瓣环直径,还决定瓣环形态。需要更长时间的随访来确定生存率的差异。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验