Diamant M, Croiset G, De Zwart N, De Wied D
Rudolf Magnus Institute, Medical Faculty, University of Utrecht, The Netherlands.
Physiol Behav. 1991 Jul;50(1):23-31. doi: 10.1016/0031-9384(91)90493-8.
Heart rate (HR), core temperature (CT) and gross locomotor activity (GLA) were recorded in rats by a computerized telemetry system before, during and after 15-min exposure to a constantly electrified (2mA) or nonelectrified (0mA) prod which was presented through a hole in the home cage with woodshavings on the floor [shock-prod burying (SPB) test]. Measurement of both autonomic and behavioral response continued up to 60 min after introduction of the prod in the home cage. Twenty-four h after the SPB test, rats were tested for retention. During the SPB test, significant increases in HR, respective to baseline values, were observed in both the 2mA and 0mA group, but the tachycardiac response in the former group significantly outweighed that in the latter group. In shocked rats, HR remained elevated during the entire 45-min posttest period, whereas HR declined immediately after removal of the prod in nonshocked animals. An onset in rise in CT was observed in the 2mA, but not in the 0mA group, during prod exposure time, which eventually resulted in an additional-more than two-fold--increase after termination of the test and outlasted total recording time. Marked behavioral activation was observed in the 2mA group, whereas the 0mA responded to a lesser extent. Approach and exploration of the prod was reduced when the prod was electrified. The total time spent by rats burying the prod was significantly longer in the shocked than in the nonshocked group. When exposed to the nonelectrified prod after 24 h, total burying time was reduced in the 2mA group but still significantly longer than in the 0mA group.(ABSTRACT TRUNCATED AT 250 WORDS)
在大鼠通过计算机遥测系统记录心率（HR）、核心体温（CT）和总体运动活动（GLA），记录时间为在通过置于铺有木屑的饲养笼上的孔洞呈现持续通电（2mA）或不通电（0mA）的刺激棒之前、期间和之后15分钟[电击棒掩埋（SPB）试验]。在将刺激棒放入饲养笼后，自主神经和行为反应的测量持续60分钟。SPB试验24小时后，对大鼠进行记忆测试。在SPB试验期间，2mA组和0mA组的HR相对于基线值均显著增加，但前一组的心动过速反应明显超过后一组。在受电击的大鼠中，在整个45分钟的测试后期间HR保持升高，而在未受电击的动物中，移除刺激棒后HR立即下降。在刺激棒暴露期间，2mA组观察到CT开始上升，而0mA组未观察到，这最终导致在试验结束后CT额外增加两倍以上，并持续超过总记录时间。在2mA组观察到明显的行为激活，而0mA组反应程度较小。当刺激棒通电时，对其的接近和探索减少。受电击组大鼠掩埋刺激棒的总时间明显长于未受电击组。在24小时后暴露于不通电的刺激棒时，2mA组的总掩埋时间减少，但仍明显长于0mA组。（摘要截断于250字）
