与脊柱关节病相关的胃肠道病变。
Gastrointestinal lesions associated with spondyloarthropathies.
作者信息
Orlando Ambrogio, Renna Sara, Perricone Giovanni, Cottone Mario
机构信息
Department of General Medicine, Pneumology and Nutrition Clinic, V Cervello Hospital, Palermo University, Palermo, Italy.
出版信息
World J Gastroenterol. 2009 May 28;15(20):2443-8. doi: 10.3748/wjg.15.2443.
Abstract
Subclinical gut inflammation has been described in up to two-thirds of patients with spondyloarthropathies (SpA). Arthritis represents an extra-intestinal manifestation of several gastrointestinal diseases, including inflammatory bowel disease (IBD), Whipple's disease, Behcet's disease, celiac disease, intestinal bypass surgery, parasitic infections of the gut and pseudomembranous colitis. Moreover about two-thirds of nonsteroidal anti-inflammatory drug users demonstrate intestinal inflammation. Arthritis may manifest as a peripheral or axial arthritis. The spondyloarthropathy family consists of the following entities: ankylosing spondylitis, undifferentiated spondyloarthritis, reactive arthritis, psoriatic arthritis, spondyloarthritis associated with IBD, juvenile onset spondyloarthritis. This topic reviews the major gastrointestinal manifestations that can occur in patients with SpA and in nonsteroidal anti-inflammatory drugs users.
摘要
高达三分之二的脊柱关节病（SpA）患者存在亚临床肠道炎症。关节炎是几种胃肠道疾病的肠外表现，包括炎症性肠病（IBD）、惠普尔病、白塞病、乳糜泻、肠道旁路手术、肠道寄生虫感染和伪膜性结肠炎。此外，约三分之二的非甾体抗炎药使用者存在肠道炎症。关节炎可表现为外周性或轴索性关节炎。脊柱关节病家族包括以下几种疾病：强直性脊柱炎、未分化脊柱关节炎、反应性关节炎、银屑病关节炎、与IBD相关的脊柱关节炎、青少年起病的脊柱关节炎。本主题综述了SpA患者和非甾体抗炎药使用者可能出现的主要胃肠道表现。
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