Rakhimova O Iu
Klin Med (Mosk). 2009;87(3):11-8.
Studies on the role and the use of melatonin in the treatment of various diseases are considered to be of great interest to date. Melatonin is a hormone with unique adaptive potential; its abnormal production and secretion rhythm trigger the mechanism of desynchronosis leading to organic pathology. Impaired melatonin secretion is observed in subjects with insomnia, cardiovascular and digestive disorders, it occurs during seasonal exacerbation of chronic diseases and in patients with hormone-dependent tumours. Understanding the role of melatonin in pathogenesis of different diseases may facilitate its use for the treatment of various disorders.
迄今为止，褪黑素在各种疾病治疗中的作用及应用研究备受关注。褪黑素是一种具有独特适应潜力的激素；其异常的产生和分泌节律会触发失同步机制，进而导致器质性病变。在失眠、心血管和消化系统疾病患者中可观察到褪黑素分泌受损，在慢性病的季节性加重期以及激素依赖性肿瘤患者中也会出现这种情况。了解褪黑素在不同疾病发病机制中的作用可能有助于其用于治疗各种疾病。
