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黄斑淋巴细胞性动脉炎:一种独特的良性皮肤动脉炎,由淋巴细胞介导,表现为黄斑。

Macular lymphocytic arteritis: a unique benign cutaneous arteritis, mediated by lymphocytes and appearing as macules.

作者信息

Saleh Zenus, Mutasim Diya F

机构信息

Department of Dermatology, University of Cincinnati, Cincinnati, OH 45267-0592, USA.

出版信息

J Cutan Pathol. 2009 Dec;36(12):1269-74. doi: 10.1111/j.1600-0560.2009.01272.x.

Abstract

BACKGROUND

Macular arteritis (MA) is a term coined for a cutaneous vasculitis that manifests as multiple macules that favor the lower extremities and that reveal lymphocytic inflammation of an artery in the deep dermis and subcutaneous fat.

METHODS

We describe the demographic, clinical, histologic, and laboratory findings in three new cases and review seven previously reported cases of MA, and discuss the nosology of MA.

RESULTS

MA affects predominantly females (70% or 7/10) and individuals of African-American race (50%). Eight patients had hyperpigmented patches, one had hypopigmented macules, and one had erythematous macules. The lower extremities were involved in 100% of cases, followed by the upper extremities (44%). Light microscopic changes are those of a medium-vessel lymphocytic arteritis. Investigations for possible causes are non-revealing.

CONCLUSION

We conclude that MA is a primary idiopathic cutaneous lymphocytic arteritis that is limited to the skin.

摘要

背景

黄斑动脉炎(MA)是一个用于描述一种皮肤血管炎的术语,其表现为多个黄斑,好发于下肢,且显示真皮深层和皮下脂肪中动脉的淋巴细胞性炎症。

方法

我们描述了3例新病例的人口统计学、临床、组织学和实验室检查结果,并回顾了7例先前报道的MA病例,同时讨论了MA的疾病分类学。

结果

MA主要影响女性(70%或7/10)和非裔美国人(50%)。8例患者有色素沉着斑,1例有色素减退斑,1例有红斑。100%的病例累及下肢,其次是上肢(44%)。光镜下改变为中等血管淋巴细胞性动脉炎。对可能病因的检查未发现异常。

结论

我们得出结论,MA是一种局限于皮肤的原发性特发性皮肤淋巴细胞性动脉炎。

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