Eghan Benjamin A, Amoako-Atta Kwabena, Kankam Charity Ama, Nsiah-Asare Anthony
Department of Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Hemodial Int. 2009 Oct;13(4):467-71. doi: 10.1111/j.1542-4758.2009.00379.x. Epub 2009 May 12.
To evaluate the survival pattern of hemodialysis patients at a dialysis unit in Kumasi, Ghana, through a retrospective (observational) study. Patients who were placed on hemodialysis at the dialysis unit at Komfo Anokye teaching hospital from October 25, 2006 to December 2007. The patients were followed from initiation of dialysis until December 31, 2007. The overall mortality was 14 (35.9%) on the incident population for the period and that for the first 90 days was 12 (32.4%) patients. Chronic glomerulonephritis was the underlying kidney disease in 35.9%. This was followed by hypertension (19.1%) and diabetes mellitus (15.4%), respectively. Cardiovascular diseases accounted for 42% of mortality. This was followed by septicemia (25%) from the access site and anemia (25%). Fifty percent of the patients were able to afford 20 sessions of hemodialysis before stopping. The most powerful predictors of survival were the duration of hemodialysis (P=0.05) and the number of hemodialysis sessions (P=0.02). Age at initiation of hemodialysis was not significant. First 90-day mortality of patients on hemodialysis is high in poor African countries. This is due partially to the late referral of patients and also the cost of the dialysis treatment. Efforts will have to be made to reduce the cost of the dialysis treatment. Reuse technology (of dialyzer, etc.) should be introduced to cut down the cost of hemodialysis. Peritoneal dialysis should also be introduced for highly motivated patients. Efforts should also be made to reduce the increasing incidence of kidney disease, and finally third-world countries should consider establishing kidney transplantation, that is cost effective.
通过一项回顾性(观察性)研究,评估加纳库马西一家透析单位血液透析患者的生存模式。研究对象为2006年10月25日至2007年12月期间在科姆福·阿诺克耶教学医院透析单位接受血液透析的患者。对患者从开始透析一直随访至2007年12月31日。该时期内,发病患者群体的总死亡率为14例(35.9%),前90天的死亡率为12例(32.4%)患者。慢性肾小球肾炎是35.9%患者的潜在肾脏疾病。其次分别是高血压(19.1%)和糖尿病(15.4%)。心血管疾病占死亡率的42%。其次是通路部位的败血症(25%)和贫血(25%)。50%的患者在停止透析前能够负担20次血液透析治疗。生存的最有力预测因素是血液透析的持续时间(P = 0.05)和血液透析治疗次数(P = 0.02)。开始血液透析时的年龄无显著影响。在贫穷的非洲国家,血液透析患者的前90天死亡率很高。部分原因是患者转诊延迟以及透析治疗费用。必须努力降低透析治疗费用。应引入透析器等的复用技术以降低血液透析成本。对于积极性高的患者也应引入腹膜透析。还应努力降低不断上升的肾脏疾病发病率,最后第三世界国家应考虑开展具有成本效益的肾脏移植。