Brenes Gretchen A, Miller Michael E, Stanley Melinda A, Williamson Jeff D, Knudson Mark, McCall W Vaughn
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
Am J Geriatr Psychiatry. 2009 Jun;17(6):465-72. doi: 10.1097/jgp.0b013e3181987747.
The purposes of this study are to determine the frequency and severity of insomnia symptoms and related complaints experienced by older adults with Generalized Anxiety Disorder (GAD) and compare them with older adults without GAD; compare insomnia symptoms among older adults with GAD with and without comorbid depression; determine if there are age differences in insomnia severity among people with GAD; and determine if there are differences in insomnia severity between older adults with GAD and older adults diagnosed with insomnia.
Cross-sectional.
Participants were recruited through primary care clinics, advertisements, and mass mailings.
One hundred ten older adults; 31 with GAD, 25 with GAD and depression, 33 worried well, and 21 with no psychiatric diagnosis.
Psychiatric diagnosis, sleep disturbance, and health.
Participants with GAD with and without comorbid depression reported significantly greater sleep disturbance severity than participants with no psychiatric diagnosis and the worried well. There were no differences in sleep disturbances between older adults with GAD only and older adults with comorbid GAD and depression. The severity of sleep disturbance reported by older participants with GAD was greater than reports by young and middle-aged participants with GAD, and comparable with reports by older adults with a diagnosis of insomnia.
Ninety percent of older adults with GAD report dissatisfaction with sleep and the majority report moderate to severe insomnia. These findings support the assessment of sleep disturbances within the context of late-life GAD.
本研究旨在确定广泛性焦虑障碍(GAD)老年患者失眠症状及相关主诉的发生频率和严重程度,并将其与无GAD的老年人进行比较;比较合并或未合并抑郁症的GAD老年患者的失眠症状;确定GAD患者的失眠严重程度是否存在年龄差异;以及确定GAD老年患者与被诊断为失眠的老年患者在失眠严重程度上是否存在差异。
横断面研究。
通过初级保健诊所、广告和大规模邮件招募参与者。
110名老年人;31名患有GAD,25名患有GAD且合并抑郁症,33名健康担忧者,21名无精神疾病诊断者。
精神疾病诊断、睡眠障碍和健康状况。
合并或未合并抑郁症的GAD参与者报告的睡眠障碍严重程度显著高于无精神疾病诊断者和健康担忧者。仅患有GAD的老年人与合并GAD和抑郁症的老年人在睡眠障碍方面没有差异。患有GAD的老年参与者报告的睡眠障碍严重程度高于患有GAD的青年和中年参与者,且与被诊断为失眠的老年参与者的报告相当。
90%的GAD老年患者报告对睡眠不满意,大多数报告有中度至重度失眠。这些发现支持在老年期GAD的背景下对睡眠障碍进行评估。