Song Haijun, Bowsher James, Das Shiva, Yin Fang-Fang
Department of Radiation Oncology, Duke University, Durham, North Carolina 27710, USA.
Med Phys. 2009 Apr;36(4):1109-11. doi: 10.1118/1.3081402.
This work proposes to use the radiation from brachytherapy sources to track their dwell positions in three-dimensional (3D) space. The prototype device uses a single flat panel detector and a BB tray. The BBs are arranged in a defined pattern. The shadow of the BBs on the flat panel is analyzed to derive the 3D coordinates of the illumination source, i.e., the dwell position of the brachytherapy source. A kilovoltage x-ray source located 3.3 m away was used to align the center BB with the center pixel on the flat panel detector. For a test plan of 11 dwell positions, with an Ir-192 high dose rate unit, one projection was taken for each dwell point, and locations of the BB shadows were manually identified on the projection images. The 3D coordinates for the 11 dwell positions were reconstructed based on two BBs. The distances between dwell points were compared with the expected values. The average difference was 0.07 cm with a standard deviation of 0.15 cm. With automated BB shadow recognition in the future, this technique possesses the potential of tracking the 3D trajectory and the dwell times of a brachytherapy source in real time, enabling real time source position verification.
这项工作提议利用近距离放射治疗源的辐射来追踪其在三维(3D)空间中的驻留位置。该原型设备使用单个平板探测器和一个铅珠托盘。铅珠按规定模式排列。分析平板上铅珠的阴影,以得出照明源的3D坐标,即近距离放射治疗源的驻留位置。使用距离3.3米远的千伏级X射线源将中心铅珠与平板探测器上的中心像素对齐。对于一个有11个驻留位置的测试计划,使用铱-192高剂量率装置,每个驻留点拍摄一张投影图像,并在投影图像上手动识别铅珠阴影的位置。基于两个铅珠重建了11个驻留位置的3D坐标。将驻留点之间的距离与预期值进行比较。平均差值为0.07厘米,标准差为0.15厘米。未来随着铅珠阴影的自动识别,该技术具有实时追踪近距离放射治疗源的3D轨迹和驻留时间的潜力,从而实现实时源位置验证。