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使用二维探测器阵列IMatriXX在高剂量率近距离放射治疗中的相对剂量验证。

Relative dosimetrical verification in high dose rate brachytherapy using two-dimensional detector array IMatriXX.

作者信息

Manikandan A, Biplab Sarkar, David Perianayagam A, Holla R, Vivek T R, Sujatha N

机构信息

Department of Radiation Oncology, Narayana Hrudayalaya, Bangalore, India.

出版信息

J Med Phys. 2011 Jul;36(3):171-5. doi: 10.4103/0971-6203.83491.

Abstract

For high dose rate (HDR) brachytherapy, independent treatment verification is needed to ensure that the treatment is performed as per prescription. This study demonstrates dosimetric quality assurance of the HDR brachytherapy using a commercially available two-dimensional ion chamber array called IMatriXX, which has a detector separation of 0.7619 cm. The reference isodose length, step size, and source dwell positional accuracy were verified. A total of 24 dwell positions, which were verified for positional accuracy gave a total error (systematic and random) of -0.45 mm, with a standard deviation of 1.01 mm and maximum error of 1.8 mm. Using a step size of 5 mm, reference isodose length (the length of 100% isodose line) was verified for single and multiple catheters of same and different source loadings. An error ≤1 mm was measured in 57% of tests analyzed. Step size verification for 2, 3, 4, and 5 cm was performed and 70% of the step size errors were below 1 mm, with maximum of 1.2 mm. The step size ≤1 cm could not be verified by the IMatriXX as it could not resolve the peaks in dose profile.

摘要

对于高剂量率(HDR)近距离放射治疗,需要进行独立的治疗验证,以确保治疗按照处方进行。本研究展示了使用一种名为IMatriXX的商用二维电离室阵列对HDR近距离放射治疗进行剂量学质量保证,该阵列的探测器间距为0.7619厘米。对参考等剂量长度、步长和源驻留位置精度进行了验证。总共24个驻留位置的位置精度得到验证,总误差(系统误差和随机误差)为-0.45毫米,标准差为1.01毫米,最大误差为1.8毫米。使用5毫米的步长,对相同和不同源加载的单根和多根导管的参考等剂量长度(100%等剂量线的长度)进行了验证。在分析的测试中,57%的测试测量误差≤1毫米。对2、3、4和5厘米的步长进行了验证,70%的步长误差低于1毫米,最大为1.2毫米。IMatriXX无法验证步长≤1厘米的情况,因为它无法分辨剂量剖面中的峰值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1a0/3159223/c3fc7f4c1fb5/JMP-36-171-g001.jpg

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