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一种用于近距离放射治疗施源器调试的新型系统:环形施源器示例。

A novel system for commissioning brachytherapy applicators: example of a ring applicator.

作者信息

Fonseca Gabriel P, Van den Bosch Michiel R, Voncken Robert, Podesta Mark, Verhaegen Frank

机构信息

Department of Radiation Oncology (MAASTRO), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Dr. Tanslaan 12, Maastricht 6229 ET, Netherlands.

出版信息

Phys Med Biol. 2017 Oct 19;62(21):8360-8375. doi: 10.1088/1361-6560/aa8d0a.

Abstract

A novel system was developed to improve commissioning and quality assurance of brachytherapy applicators used in high dose rate (HDR). It employs an imaging panel to create reference images and to measure dwell times and dwell positions. As an example: two ring applicators of the same model were evaluated. An applicator was placed on the surface of an imaging panel and a HDR Ir source was positioned in an imaging channel above the panel to generate an image of the applicator, using the gamma photons of the brachytherapy source. The applicator projection image was overlaid with the images acquired by capturing the gamma photons emitted by the source dwelling inside the applicator. We verified 0.1, 0.2, 0.5 and 1.0 cm interdwell distances for different offsets, applicator inclinations and transfer tube curvatures. The data analysis was performed using in-house developed software capable of processing the data in real time, defining catheters and creating movies recording the irradiation procedure. One applicator showed up to 0.3 cm difference from the expected position for a specific dwell position. The problem appeared intermittently. The standard deviations of the remaining dwell positions (40 measurements) were less than 0.05 cm. The second ring applicator had a similar reproducibility with absolute coordinate differences from expected values ranging from  -0.10 up to 0.18 cm. The curvature of the transfer tube can lead to differences larger than 0.1 cm whilst the inclination of the applicator showed a negligible effect. The proposed method allows the verification of all steps of the irradiation, providing accurate information about dwell positions and dwell times. It allows the verification of small interdwell positions (⩽0.1 cm) and reduces measurement time. In addition, no additional radiation source is necessary since the HDR Ir source is used to generate an image of the applicator.

摘要

开发了一种新型系统,以改善高剂量率(HDR)近距离放射治疗施源器的调试和质量保证。它采用成像板来创建参考图像,并测量驻留时间和驻留位置。例如:对两个相同型号的环形施源器进行了评估。将一个施源器放置在成像板表面,并将一个HDR铱源定位在成像板上方的成像通道中,利用近距离放射治疗源的伽马光子生成施源器的图像。施源器投影图像与通过捕获源驻留在施源器内时发射的伽马光子所获取的图像进行叠加。我们针对不同的偏移、施源器倾斜度和传输管曲率,验证了0.1、0.2、0.5和1.0厘米的驻留间距。使用内部开发的能够实时处理数据、定义导管并创建记录照射过程的影片的软件进行数据分析。对于特定的驻留位置,一个施源器与预期位置的差异高达0.3厘米。该问题间歇性出现。其余驻留位置(40次测量)的标准偏差小于0.05厘米。第二个环形施源器具有类似的再现性,与预期值的绝对坐标差异范围为-0.10至0.18厘米。传输管的曲率可能导致差异大于0.1厘米,而施源器的倾斜度影响可忽略不计。所提出的方法允许验证照射的所有步骤,提供有关驻留位置和驻留时间的准确信息。它允许验证小的驻留间距(≤0.1厘米)并减少测量时间。此外,由于使用HDR铱源来生成施源器的图像,因此无需额外的辐射源。

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