Bittner James G, Sajadi Kamran, Brown James A
Department of Surgery, Medical College of Georgia, School of Medicine, Augusta, GA 30912, USA.
J Endourol. 2009 Jun;23(6):933-7. doi: 10.1089/end.2008.0297.
This study assessed differences in outcomes between left renal artery clipping and stapling techniques in hand-assisted laparoscopic living donor nephrectomy (HALDN).
From 2003 to 2007, 55 HALDN procedures were performed by one laparoscopy-trained urologist. During the first 30 months, 27 consecutive HALDN patients underwent renal artery occlusion with two nonabsorbable polymer locking clips (group 1). The subsequent 18 months saw 28 consecutive HALDN patients receive three-row vascular stapling to occlude the renal artery (group 2). The preoperative patient factors were age, sex, body mass index, serum creatinine (Cr), and presence of supernumerary left renal artery. Intraoperative factors included estimated blood loss (EBL), operative time (OT), and warm ischemia time (WIT). Postoperative data were 24-hour Cr and hemoglobin concentration, transfusion requirement, hospitalization time, and complications. Data are presented as mean +/- standard deviation and analyzed using parametric tests (alpha = 0.05).
No significant difference was found between groups with respect to preoperative factors, OT, and EBL; however, WIT was shorter in group 2 (3.6 +/- 0.2 vs 2.6 +/- 0.3, P = 0.048). Within-group comparisons revealed longer WIT for patients with supernumerary renal artery compared with those with a single artery (group 1, P = 0.044; group 2, P = 0.042). Moreover, no major between-group variations were seen in postoperative donor outcomes.
Left renal artery ligation during HALDN using a three-row vascular stapler is safe and yields donor outcomes comparable to dual polymer clips. In addition, left renal artery stapling may decrease WIT compared with dual clipping.
本研究评估了手辅助腹腔镜活体供肾肾切除术(HALDN)中左肾动脉夹闭术与吻合器技术在手术结果上的差异。
2003年至2007年期间,由一名经过腹腔镜培训的泌尿科医生实施了55例HALDN手术。在最初的30个月里,27例连续的HALDN患者接受了用两个不可吸收聚合物锁定夹进行肾动脉阻断(第1组)。在随后的18个月里,28例连续的HALDN患者接受了三排血管吻合器进行肾动脉阻断(第2组)。术前患者因素包括年龄、性别、体重指数、血清肌酐(Cr)以及是否存在额外的左肾动脉。术中因素包括估计失血量(EBL)、手术时间(OT)和热缺血时间(WIT)。术后数据包括24小时Cr和血红蛋白浓度、输血需求、住院时间以及并发症。数据以平均值±标准差表示,并使用参数检验进行分析(α = 0.05)。
两组在术前因素、OT和EBL方面未发现显著差异;然而,第2组的WIT较短(3.6±0.2对2.6±0.3,P = 0.048)。组内比较显示,与单支动脉患者相比,有额外肾动脉的患者WIT更长(第1组,P = 0.044;第2组,P = 0.042)。此外,两组术后供体结果未见主要差异。
在HALDN中使用三排血管吻合器进行左肾动脉结扎是安全的,且供体结果与双聚合物夹相当。此外,与双夹闭相比,左肾动脉吻合器吻合可能会减少WIT。