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腹腔镜活体供肾切除术的另一种选择:单中心经验比较二孔法与手助技术。

Another option for laparoscopic living donor nephrectomy: a single center experience comparing two-port versus hand-assisted technique.

机构信息

Department of Urology, College of Medicine, Catholic University of Korea, Seoul, Korea.

出版信息

J Endourol. 2013 May;27(5):587-91. doi: 10.1089/end.2012.0577. Epub 2013 Feb 19.

DOI:10.1089/end.2012.0577
PMID:23228097
Abstract

PURPOSE

To compare the clinical outcomes of two-port laparoscopic donor nephrectomy (TPLDN) vs hand-assisted laparoscopic donor nephrectomy (HALDN).

PATIENTS AND METHODS

Between November 2010 and March 2012, 100 kidney donors scheduled for left nephrectomy were alternatively assigned to HALDN or TPLDN in a 1:1 fashion. All procedures were performed by the same laparoscopic surgeon. Demographic data and intraoperative and early postoperative data were collected prospectively and analyzed.

RESULTS

There was no difference in the operating time (133±12 vs 142±17 min, P=0.07), blood loss (55±46 vs 58±52 mL, P=0.84), complication rate (10% vs 12%, P=0.74), and length of hospital stay (3.8±0.8 vs 4.1±2.8 days, P=0.5) between the HALDN and TPLDN groups. The warm ischemia time was longer in the TPLDN group (2.2±0.7 vs 3.5±0.9 min, P<0.001). No statistically significant differences were found in the analgesic requirement and the visual analog pain scores. There was a trend toward quicker return to 100% recovery in the TPLDN group (60±46 vs 39±15 days, P=0.05). The TPLDN group had a significantly smaller surgical incision (8.2±0.6 vs 5.5±0.4 cm, P<0.001) and higher scar satisfaction score (7.8±1.5 vs 8.6±1.3, P=0.02) than the HALDN group. No differences were found in the recipient serum creatinine values or in the incidence of delayed graft function.

CONCLUSIONS

In comparing TPLDN and HALDN, there was no significant difference in a majority of the operative and postoperative parameters. TPLDN might be associated with smaller surgical incision, improved cosmetic satisfaction, and equivalent recipient graft function.

摘要

目的

比较两孔腹腔镜供肾切取术(TPLDN)与手助腹腔镜供肾切取术(HALDN)的临床效果。

方法

2010 年 11 月至 2012 年 3 月,100 例拟行左肾切除术的供肾者被按 1:1 的比例随机分配至 HALDN 或 TPLDN 组。所有手术均由同一位腹腔镜外科医师完成。前瞻性收集并分析了供者的人口统计学资料以及围手术期和早期术后数据。

结果

两组的手术时间(133±12 分钟比 142±17 分钟,P=0.07)、术中出血量(55±46 毫升比 58±52 毫升,P=0.84)、并发症发生率(10%比 12%,P=0.74)和住院时间(3.8±0.8 天比 4.1±2.8 天,P=0.5)均无差异。TPLDN 组的热缺血时间较长(2.2±0.7 分钟比 3.5±0.9 分钟,P<0.001)。两组的镇痛需求和视觉模拟疼痛评分无统计学差异。TPLDN 组更快恢复至 100%(60±46 天比 39±15 天,P=0.05)。TPLDN 组的手术切口更小(8.2±0.6 厘米比 5.5±0.4 厘米,P<0.001),瘢痕满意度评分更高(7.8±1.5 分比 8.6±1.3 分,P=0.02)。两组受者的血清肌酐值或延迟移植物功能发生率均无差异。

结论

与 HALDN 相比,TPLDN 在大多数手术和术后参数方面无显著差异。TPLDN 可能具有更小的手术切口、改善的美容满意度和等效的受者移植物功能。

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