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与未识别的起搏适应证相关的延误和不良临床结局。

Delays and adverse clinical outcomes associated with unrecognized pacing indications.

作者信息

Cunnington M S, Plummer C J, McComb J M

机构信息

Department of Cardiology, Freeman Hospital, Freeman Road, Newcastle upon Tyne, UK.

出版信息

QJM. 2009 Jul;102(7):485-90. doi: 10.1093/qjmed/hcp066. Epub 2009 May 27.

Abstract

BACKGROUND

A recent UK audit showed that a significant proportion of patients who received pacemakers had pacing indications previously overlooked, leading to significant delays to pacemaker implantation.

AIM

To investigate the reasons for, and morbidity associated with, overlooked pacing indications.

DESIGN

Prospective observational study in a UK regional pacing centre and its referring district hospitals.

METHODS

Hospital records from referring and implanting centres were reviewed for 95 consecutive patients undergoing first pacemaker implant to determine symptoms, investigations and hospitalisations occurring after documentation of a pacing indication.

RESULTS

Thirty-three of ninety-five patients (35%) had a pacing indication overlooked, which was Class I in 14 patients and Class IIa in 19. Reasons for not making a pacing referral in these patients included: failure to recognize the indication in 14, making adjustments to potentially culprit medication in 15 and requesting additional 'confirmatory' tests in 4. Twenty-six patients (79%) with missed indications experienced adverse events after documentation of an indication, and before receiving a pacemaker: 23 had ongoing symptoms (including one cardiac arrest), three received temporary pacing wires and 18 were hospitalized with symptoms related to cardiac rhythm. Twenty-seven patients (82%) had a total of 38 additional specialist investigations after documentation of a pacing indication.

CONCLUSION

Documentation of an indication for pacing failed to trigger referral for permanent pacing in 35% of patients. This failure led to significant delays, morbidity and use of health service resource, which may have been avoided if timely recognition of the pacing indication had prompted referral. Failure to recognize pacing indications and reassessing symptoms and repeating investigation after changes to medication, often required for the management of associated tachyarrhythmias or other medical conditions, contribute to these delays, perhaps unnecessarily.

摘要

背景

英国近期一项审计显示,接受起搏器治疗的患者中有很大一部分先前被忽视了起搏指征,导致起搏器植入严重延迟。

目的

调查被忽视的起搏指征的原因及相关发病率。

设计

在英国一个地区起搏中心及其转诊的地区医院进行的前瞻性观察性研究。

方法

回顾了来自转诊中心和植入中心的医院记录,涉及95例连续接受首次起搏器植入的患者,以确定在记录起搏指征后出现的症状、检查和住院情况。

结果

95例患者中有33例(35%)的起搏指征被忽视,其中14例为I类指征,19例为IIa类指征。这些患者未进行起搏转诊的原因包括:14例未识别出指征,15例对可能的致病药物进行了调整,4例要求进行额外的“确认性”检查。26例(79%)有漏诊指征的患者在记录指征后、接受起搏器之前发生了不良事件:23例有持续症状(包括1例心脏骤停),3例接受了临时起搏导线,18例因与心律相关的症状住院。27例(82%)患者在记录起搏指征后共进行了38项额外的专科检查。

结论

35%的患者在记录起搏指征后未能触发永久性起搏转诊。这种未能转诊导致了严重的延迟、发病率增加和卫生服务资源的使用,如果及时识别起搏指征并促使转诊,这些情况可能是可以避免的。未能识别起搏指征以及在调整药物(这通常是治疗相关快速心律失常或其他疾病所必需的)后重新评估症状和重复检查,导致了这些延迟,或许是不必要的。

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