Department of Pediatrics,Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.
Indian J Pediatr. 2009 Aug;76(8):843-5. doi: 10.1007/s12098-009-0148-4. Epub 2009 May 27.
We report 3 cases of Visceral leishmaniasis, who presented with unusual clinical manifestations. One child was diagnosed as hemophagocytic syndrome; another masqueraded with features of leukemoid changes alongwith hemophagocytosis and trilineage myelodysplasia; the third case presented with pyothorax. All the three patients showed amastigote forms of Leishmania donovani and positive serology (rk39 antigen). They showed complete clinical, hematological and parasitological resolution with Amphotericin B therapy.
我们报告了 3 例内脏利什曼病患者,他们表现出不同寻常的临床表现。一名儿童被诊断为噬血细胞综合征;另一名则表现为类白血病改变,伴有噬血现象和三系骨髓发育不良;第三例表现为脓胸。所有 3 例患者均显示出杜氏利什曼原虫的无鞭毛体形式和阳性血清学(rk39 抗原)。他们在接受两性霉素 B 治疗后完全缓解了临床、血液学和寄生虫学症状。