4.5 月龄婴儿感染 H1N1 病毒和内脏利什曼病相关噬血细胞性淋巴组织细胞增生症
Hemophagocytic lymphohistiocytosis associated with H1N1 virus infection and visceral leishmaniasis in a 4.5-month-old infant.
机构信息
Division of Pediatric Hematology, Ege University Medical Faculty, Izmir, Turkey.
出版信息
Rev Soc Bras Med Trop. 2012 Jun;45(3):407-9.
PMID:22760147
Abstract
We present a case of a 4.5-month-old boy from Turkey with hemophagocytic lymphohistiocytosis (HLH) associated with H1N1 virus and Leishmania spp. coinfection. Because visceral leishmaniasis can mimic hematologic disorders like HLH, it is important to rule out this clinical condition before starting immunosuppressive therapy. In our case, treatment with liposomal amphotericin B resulted in a dramatic resolution of clinical and laboratory abnormalities.
摘要
我们报告了一例来自土耳其的 4.5 个月大男婴，其患有与 H1N1 病毒和利什曼原虫属混合感染相关的噬血细胞性淋巴组织细胞增生症（HLH）。由于内脏利什曼病可能类似于 HLH 等血液系统疾病，因此在开始免疫抑制治疗之前，排除这种临床情况非常重要。在我们的病例中，用脂质体两性霉素 B 治疗导致临床和实验室异常显著缓解。
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