Department of Epidemiology, Maastricht University, Maastricht, The Netherlands.
Neurourol Urodyn. 2010 Mar;29(3):336-43. doi: 10.1002/nau.20752.
To identify prognostic indicators independently associated with poor outcome of physiotherapy intervention in women with primary or recurrent stress urinary incontinence (stress UI).
A prospective cohort study was performed in physiotherapy practices in primary care to identify prognostic indicators 12 weeks after initiation of physiotherapy intervention. Patients were referred by general practitioners or urogynecologists. Risk factors for stress UI were examined as potential prognostic indicators of poor outcome. The primary outcomes were defined as poor outcome on the binary Leakage Severity scale (LS scale) and the binary global perceived effectiveness (GPE) score.
Two hundred sixty-seven women, with a mean age of 47.7 (SD = 8.3), with stress UI for at least 6 months were included. At 12 weeks, 43% and 59% of the women were considered recovered on the binary LS scale and the binary GPE score, respectively. Prognostic indicators associated with poor outcome included 11 indicators based on the binary LS scale and 8 based on the binary GPE score. The prognostic indicators shared by both models show that poor recovery was associated with women with severe stress UI, POP-Q stage > II, poor outcome of physiotherapy intervention for a previous UI episode, prolonged second stage of labor, BMI > 30, high psychological distress, and poor physical health.
This study provides robust evidence of clinically meaningful prognostic indicators of poor short-term outcome. These findings need to be confirmed by replication studies.
确定与原发性或复发性压力性尿失禁(压力性尿失禁)女性物理治疗干预效果差相关的独立预后指标。
在初级保健中的物理治疗实践中进行了一项前瞻性队列研究,以确定物理治疗干预开始后 12 周的预后指标。患者由全科医生或泌尿科医生转介。将压力性尿失禁的危险因素作为预后不良的潜在预后指标进行检查。主要结局定义为二元漏尿严重程度量表(LS 量表)和二元总体感知疗效(GPE)评分的不良结局。
共纳入 267 名年龄平均为 47.7(SD=8.3)岁、压力性尿失禁至少 6 个月的女性。12 周时,43%和 59%的女性分别在二元 LS 量表和二元 GPE 评分上被认为恢复。与不良结局相关的预后指标包括基于二元 LS 量表的 11 个指标和基于二元 GPE 评分的 8 个指标。两个模型共有的预后指标表明,严重压力性尿失禁、POP-Q 期>II、先前 UI 发作的物理治疗干预效果差、第二产程延长、BMI>30、心理困扰严重和身体健康状况差的女性恢复不佳。
本研究提供了与短期预后不良相关的具有临床意义的预后指标的有力证据。这些发现需要通过复制研究来证实。