Kalaitzi Marina, Papaefstathiou Efstathios, Gatsos Sotirios, Giannakodimos Ilias, Apostolidis Ioannis, Konstantinidou Eleni, Mytilekas Konstantinos-Vaios, Ioannidou Eleni, Mikos Themistoklis, Apostolidis Apostolos
2 Department of Urology, School of Medicine, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, 56429 Greece.
Department of Pelvic Floor Physiotherapy, Alexandrion Technological Educational Institute of Thessaloniki, Sindos, Thessaloniki, 57400 Greece.
Bladder (San Franc). 2024 Dec 12;11(4):e21200021. doi: 10.14440/bladder.2024.0032. eCollection 2024.
Factors predictive of the efficacy of pelvic floor muscle training (PFMT) in stress urinary incontinence (SUI) or mixed urinary incontinence (MUI) are poorly defined. Identifying these factors is crucial for guiding treatment decisions, determining training repetitions, and predicting PFMT outcomes.
This study aimed to identify clinical factors predictive of PFMT outcomes in women with primary SUI.
We retrospectively reviewed data from 188 consecutive women with either SUI ( = 90) or MUI ( = 98) with a primary stress component. All participants underwent a 3-month PFMT program. Predictive factors for 50% improvement and complete cure of incontinence were assessed through urogynecological history/examination, medical history, digital pelvic floor muscle (PFM) evaluation ( = 87), and 3-day bladder diaries. Logistic regression analyses were conducted for the overall group and separately for the SUI and MUI subpopulations.
At 3 months, 10% of SUI patients and 11.2% of MUI patients achieved complete SUI cure, while 35.7% of MUI patients were free from urge urinary incontinence (UUI). A complete cure of SUI was correlated with a negative or mildly positive results of stress test ( = 0.014). For MUI patients, complete UUI cure was linked to initial digital PFM evaluation results ( = 0.003) and negative ( = 0.005) or mildly positive findings of stress tests ( = 0.003). The absence of prior surgery and digital evaluation predicted a 50% improvement in MUI ( = 0.021 and = 0.026, respectively). Endurance improvement was related independently with >50% improvement in MUI patients (odds ratio = 3.794, = 0.019).
Negative or mildly positive stress tests and digital PFM evaluation predict better outcomes with PFMT. Further prospective studies are needed to validate these findings.
压力性尿失禁(SUI)或混合性尿失禁(MUI)中盆底肌训练(PFMT)疗效的预测因素尚不明确。识别这些因素对于指导治疗决策、确定训练次数以及预测PFMT结果至关重要。
本研究旨在确定原发性SUI女性中PFMT结果的临床预测因素。
我们回顾性分析了188例连续性SUI(n = 90)或MUI(n = 98)且以压力性尿失禁为主的女性患者的数据。所有参与者均接受了为期3个月的PFMT计划。通过泌尿妇科病史/检查、病史、数字化盆底肌(PFM)评估(n = 87)和3天膀胱日记,评估尿失禁改善50%和完全治愈的预测因素。对总体组以及SUI和MUI亚组分别进行逻辑回归分析。
3个月时,10%的SUI患者和11.2%的MUI患者实现了SUI的完全治愈,而35.7%的MUI患者无急迫性尿失禁(UUI)。SUI的完全治愈与压力试验阴性或轻度阳性结果相关(P = 0.014)。对于MUI患者,UUI的完全治愈与初始数字化PFM评估结果相关(P = 0.003)以及压力试验阴性(P = 0.005)或轻度阳性结果相关(P = 0.003)。既往无手术史和数字化评估预测MUI改善50%(分别为P = 0.021和P = 0.026)。耐力改善与MUI患者改善>50%独立相关(优势比 = 3.794,P = 0.019)。
压力试验阴性或轻度阳性以及数字化PFM评估预测PFMT有更好的结果。需要进一步的前瞻性研究来验证这些发现。