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Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer.

作者信息

Parker William B

机构信息

Southern Research Institute, 2000 Ninth Avenue, South Birmingham, Alabama 35205, USA.

出版信息

Chem Rev. 2009 Jul;109(7):2880-93. doi: 10.1021/cr900028p.

DOI:10.1021/cr900028p
PMID:19476376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2827868/
Abstract
摘要

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Prodrug cancer gene therapy.前体药物癌症基因治疗。
Cancer Lett. 2008 Nov 8;270(2):191-201. doi: 10.1016/j.canlet.2008.04.023. Epub 2008 May 27.
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Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair.
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RSC Adv. 2025 Jun 25;15(27):21604-21638. doi: 10.1039/d5ra02893k. eCollection 2025 Jun 23.
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Glucose- and glutamine-driven de novo nucleotide synthesis facilitates WSSV replication in shrimp.葡萄糖和谷氨酰胺驱动的从头核苷酸合成促进对虾中白斑综合征病毒的复制。
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Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies.抑制嘌呤核苷磷酸化酶作为B细胞淋巴恶性肿瘤的一种新型治疗方法。
Semin Oncol. 2007 Dec;34(6 Suppl 5):S29-34. doi: 10.1053/j.seminoncol.2007.11.004.
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Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine.三种治疗急性淋巴细胞白血病的新药:奈拉滨、氯法拉滨和福达华。
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Troxacitabine in acute leukemia.曲沙他滨治疗急性白血病
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