Division of Gastroenterology and Liver Diseases, George Washington University Medical Center, Washington, DC 20037, USA.
Am J Mens Health. 2010 Mar;4(1):71-4. doi: 10.1177/1557988308329744. Epub 2009 Feb 2.
Osteoporosis is underdiagnosed in men, and osteoporosis-related fractures carry high morbidity and mortality. Recent recommendations on osteoporosis screening in men from the American College of Physicians state that screening and risk factor assessment need to occur earlier in men at high risk. Men with inflammatory bowel disease are at high risk for osteoporosis and fragility fractures due to corticosteroid use, malabsorption from intestinal resection, potential vitamin D deficiency, and fluctuations in weight. This study examines the rate of corticosteroid use, vitamin D screening, and bone mineral density screening of men with inflammatory bowel disease in a gastroenterology practice. The vast majority of men with inflammatory bowel disease are at high risk for osteoporosis. Screening and risk factor assessment should be emphasized.
男性骨质疏松症的诊断率较低,且与骨质疏松症相关的骨折具有较高的发病率和死亡率。美国医师学院最近发布的男性骨质疏松症筛查建议指出,高危男性需要更早进行筛查和危险因素评估。由于使用皮质类固醇、肠切除导致的吸收不良、潜在的维生素 D 缺乏以及体重波动,患有炎症性肠病的男性有发生骨质疏松症和脆性骨折的高风险。本研究在胃肠病学实践中检查了患有炎症性肠病的男性使用皮质类固醇、维生素 D 筛查和骨密度筛查的比率。绝大多数患有炎症性肠病的男性都有发生骨质疏松症的高风险。应强调进行筛查和危险因素评估。