Barbour A G
Department of Microbiology, University of Texas Health Science Center, San Antonio 78284.
Scand J Infect Dis Suppl. 1991;77:88-93.
Lyme borreliosis and relapsing fever are human diseases caused by different members of the genus Borrelia. Antigenic variation has been a well-known feature of the pathogenesis of relapsing fever for decades. More recently it has been recognized that Borrelia burgdorferi, the agent of Lyme borreliosis, also can vary its surface antigens. In this review the biology and molecular biology of antigenic variation of the pathogens in these two disorders are compared.
莱姆病和回归热是由疏螺旋体属不同成员引起的人类疾病。几十年来，抗原变异一直是回归热发病机制中一个广为人知的特征。最近人们认识到，莱姆病病原体伯氏疏螺旋体也能改变其表面抗原。在这篇综述中，对这两种疾病中病原体抗原变异的生物学和分子生物学进行了比较。
