Service d'Hépato-Gastroentérologie et de Nutrition, Hôpital Laënnec, Boulevard Laënnec, Creil, France.
Eur J Gastroenterol Hepatol. 2009 Nov;21(11):1310-3. doi: 10.1097/MEG.0b013e3283221112.
Increased ferritin levels are common in the course of chronic hepatitis C, regardless of antiviral therapy. Usually, this increase in ferritin levels has minimal clinical and biological impact, and drops after therapy discontinuation. We report here on a dramatic increase in ferritin levels in a cirrhotic patient with hepatitis C treated by ribavirin monotherapy and oral iron sulphate, and discuss the possible mechanisms of this deleterious effect.
铁蛋白水平升高在慢性丙型肝炎病程中很常见，无论是否进行抗病毒治疗。通常，这种铁蛋白水平升高对临床和生物学的影响很小，并且在治疗停止后会下降。我们在此报告一例接受利巴韦林单药治疗和口服硫酸亚铁治疗的丙型肝炎肝硬化患者铁蛋白水平的显著升高，并讨论了这种有害影响的可能机制。
