Andreasen N C
Dept. of Psychiatry, University of Iowa, Iowa City 52242.
Schizophr Bull. 1991;17(3):475-81. doi: 10.1093/schbul/17.3.475.
A variety of factors must be considered in developing assessment procedures to evaluate the cost of schizophrenia. One is the definitional problem: definitions of schizophrenia have varied over time and space, with a tendency in recent years to narrow the concept substantially. These changes in definition, which reflect the increasing scientific rigor in psychiatry, make the task of establishing base rates, assessing morbidity and mortality, and ultimately determining the cost of schizophrenia more difficult. Efforts to assess the cost of schizophrenia must also take into account the fact that its cost is not simply monetary, nor can it be conceptualized using only the cost of treatment. The overall cost of schizophrenia also includes social and psychological costs experienced by patients and family members. The concept of "the overall cost" is discussed--the sum of costs to the patient (including suffering, loss of productivity, and mortality), the cost to the family (including suffering and loss of productivity), and cost of treatment (including medications, rehabilitation services, day hospitals, inpatient facilities, etc.). At present, standardized techniques are available only for assessing some aspects of patient costs, while assessments of family and treatment costs are relatively underdeveloped. Over the long run, reduction of the overall cost of schizophrenia is most likely to come from investment in research. The most effective way to reduce the overall cost is to develop improved treatments, to identify the pathophysiology and etiology of schizophrenia, and ultimately to identify ways to prevent it from occurring.
在制定评估程序以评估精神分裂症的成本时,必须考虑多种因素。一是定义问题:精神分裂症的定义随时间和空间而变化,近年来有大幅缩小概念的趋势。这些定义的变化反映了精神病学中日益提高的科学严谨性,使得确定基础发病率、评估发病率和死亡率以及最终确定精神分裂症的成本变得更加困难。评估精神分裂症成本的工作还必须考虑到这样一个事实,即其成本不仅仅是金钱方面的,也不能仅用治疗成本来概念化。精神分裂症的总体成本还包括患者及其家庭成员所经历的社会和心理成本。文中讨论了“总体成本”的概念——患者的成本(包括痛苦、生产力丧失和死亡)、家庭的成本(包括痛苦和生产力丧失)以及治疗成本(包括药物、康复服务、日间医院、住院设施等)的总和。目前,仅存在用于评估患者成本某些方面的标准化技术,而对家庭和治疗成本的评估相对滞后。从长远来看,降低精神分裂症总体成本最有可能来自于对研究的投入。降低总体成本的最有效方法是开发更好的治疗方法,确定精神分裂症的病理生理学和病因,并最终找到预防其发生的方法。