Lenzenweger M F, Dworkin R H, Wethington E
Dept. of Human Development, Cornell University, Ithaca, NY 14853-4401.
Schizophr Bull. 1991;17(3):515-24. doi: 10.1093/schbul/17.3.515.
The present report examined the latent structure of schizophrenic phenomenology. Schizophrenic patient case histories (n = 192) were rated for positive symptoms, negative symptoms, and premorbid social adjustment and the observed covariation among these clinical features was evaluated using a model-based confirmatory factor analytic approach. Our results indicated that schizophrenic phenomenology was best characterized by three distinct underlying structures. These data provide empirical support for Strauss et al.'s (1974) three-process model, which suggests that positive symptoms, negative symptoms, and disordered premorbid personal-social relationships are three distinct classes of phenomenology possibly reflective of three relatively independent pathological processes in schizophrenia. The data are also consistent with Crow's (1980, 1985, 1987) model of schizophrenic symptomatology, differentiating social impairment from both positive and negative symptoms. The heuristic implications of these data for the development of schizophrenia are discussed and the utility of a replication of the present study is noted.
本报告研究了精神分裂症现象学的潜在结构。对192例精神分裂症患者的病历进行了阳性症状、阴性症状和病前社会适应方面的评定，并采用基于模型的验证性因素分析方法评估了这些临床特征之间观察到的协变关系。我们的结果表明，精神分裂症现象学的最佳特征是由三种不同的潜在结构组成。这些数据为施特劳斯等人（1974年）的三过程模型提供了实证支持，该模型表明阳性症状、阴性症状和病前个人-社会关系紊乱是三种不同的现象学类别，可能反映了精神分裂症中三个相对独立的病理过程。这些数据也与克劳（1980年、1985年、1987年）的精神分裂症症状学模型一致，该模型将社会功能损害与阳性和阴性症状区分开来。讨论了这些数据对精神分裂症发展的启发意义，并指出了重复本研究的效用。
