Stamyr Kristin, Vaittinen Olavi, Jaakola Janne, Guss Joseph, Metsälä Markus, Johanson Gunnar, Halonen Lauri
Work Environment Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Biomarkers. 2009 Aug;14(5):285-91. doi: 10.1080/13547500902903048.
Hydrogen cyanide (HCN) in breath has been suggested as a diagnostic tool for cyanide poisoning and for cyanide-producing bacterial infections. To distinguish elevated levels of breath HCN, baseline data are needed. Background levels of HCN were measured in mixed exhaled air from 40 healthy subjects (26 men, 14 women, age 21-61 years; detection limit: 1.5 ppb; median: 4.4 ppb; range <1.5-14 ppb) by near-infrared cavity ring down spectroscopy (CRDS). No correlation was observed with smoking habits, recent meals or age. However, female subjects had slightly higher breath levels of HCN than male subjects. CRDS has not previously been used for this purpose.
呼出气体中的氰化氢（HCN）已被提议作为氰化物中毒和产生氰化物的细菌感染的诊断工具。为了区分呼出气体中升高的HCN水平，需要基线数据。通过近红外腔衰荡光谱法（CRDS）测量了40名健康受试者（26名男性，14名女性，年龄21 - 61岁；检测限：1.5 ppb；中位数：4.4 ppb；范围<1.5 - 14 ppb）混合呼出气体中的HCN背景水平。未观察到与吸烟习惯、近期饮食或年龄之间的相关性。然而，女性受试者呼出气体中的HCN水平略高于男性受试者。此前CRDS尚未用于此目的。
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