PermaNet蚊帐在埃塞俄比亚布伊和芬塔列地区部分村庄的使用、留存率及生物功效研究
Utilization, retention and bio-efficacy studies of PermaNet in selected villages in Buie and Fentalie districts of Ethiopia.
作者信息
Fettene Messay, Balkew Meshesha, Gimblet Ciara
机构信息
Aklilu Lemma Institute of Pathobiology, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.
出版信息
Malar J. 2009 May 30;8:114. doi: 10.1186/1475-2875-8-114.
BACKGROUND
Malaria remains a major public health problem in Ethiopia. Pyrethroid-treated mosquito nets are one of the major tools available for the prevention and control of malaria transmission. PermaNet is a long-lasting insecticide-treated net (LLIN) recommended by WHO for malaria control.
OBJECTIVE
The objective of the study was to assess utilization and retention of PermaNet nets distributed for malaria control in Buie and Fentalie districts and monitor the bio-efficacy of the nets using the WHO cone bioassay test procedures.
METHODS
A cross sectional study was carried out by interviewing household heads or their representative in Buie and Fentalie districts. The two districts were selected based on a priori knowledge of variations on ethnic background and housing construction. Clusters of houses were chosen within each of the study villages for selection of households. 20 households that had received one or more PermaNet nets were chosen randomly from the clusters in each village. A total of eight used PermaNet nets were collected for the bio-efficacy test. The bio-efficacy of PermaNet nets was monitored according to the standard WHO procedures using a susceptible colony of Anopheles arabiensis to deltamethrin.
RESULTS
A total of 119 household heads were interviewed during the study. The retention rate of nets that were distributed in 2005 and 2006 season was 72%. A total of 62.2% of the interviewees claimed children under five years of age slept under LLIN, while only 50.7% of the nets were observed to be hanged inside houses when used as a proxy indicator of usage of LLIN. For the bio-efficacy test the mean knock-down was 94% and 100%, while the mean mortality rate observed after 24 hr holding period was 72.2% and 67% for Buie and Fentalie districts respectively.
CONCLUSION
The study revealed a moderately high retention of PermaNet in the study villages and effectiveness of the nets when tested according to the standard WHO procedure.
背景
疟疾仍是埃塞俄比亚的一个主要公共卫生问题。经拟除虫菊酯处理的蚊帐是预防和控制疟疾传播的主要工具之一。长效驱虫蚊帐是世界卫生组织推荐用于疟疾控制的一种长效杀虫剂处理蚊帐（LLIN）。
目的
本研究的目的是评估在布伊和芬塔利耶地区分发用于疟疾控制的长效驱虫蚊帐的使用情况和留存率，并使用世界卫生组织的锥形生物测定试验程序监测蚊帐的生物效力。
方法
通过采访布伊和芬塔利耶地区的户主或其代表进行了一项横断面研究。这两个地区是根据对种族背景和房屋建筑差异的先验知识选定的。在每个研究村庄内选择房屋群以挑选住户。从每个村庄的房屋群中随机选择20户已收到一顶或多顶长效驱虫蚊帐的家庭。总共收集了8顶用过的长效驱虫蚊帐用于生物效力测试。根据世界卫生组织的标准程序，使用对溴氰菊酯敏感的阿拉伯按蚊群体监测长效驱虫蚊帐的生物效力。
结果
在研究期间共采访了119名户主。2005年和2006年季节分发的蚊帐留存率为72%。共有62.2%的受访者称5岁以下儿童睡在长效杀虫剂处理蚊帐下，而当将其用作长效杀虫剂处理蚊帐使用情况的替代指标时，仅观察到50.7%的蚊帐挂在屋内。对于生物效力测试，布伊和芬塔利耶地区的平均击倒率分别为94%和100%，而在24小时保持期后观察到的平均死亡率分别为72.2%和67%。
结论
该研究表明，在研究村庄中长效驱虫蚊帐的留存率中等偏高，并且按照世界卫生组织标准程序测试时蚊帐具有有效性。
Zotero 插件