Patel Nirupa, Patel Neej, Espinoza Luis R
Section of Rheumatology, Louisiana State University Health Sciences Center, 2020 Gravier Street, 7th Floor, Rm 719/7D4, New Orleans, LA 70065, USA.
Rheum Dis Clin North Am. 2009 Feb;35(1):139-61. doi: 10.1016/j.rdc.2009.03.007.
In this article, the authors discuss the occurrence and prevalence of rheumatic syndromes before and after highly active antiretroviral therapy became the usual mode of treatment. The immunologic, environmental, and genetic factors behind the combination of HIV infection and rheumatic manifestation contribute to the complexity of these diseases. Miscellaneous case reports are discussed in relation to HIV infection. The authors conclude that geriatric care of HIV patients is on the horizon as more people have access to newer, more effective therapy and mortality is on the decline. Younger HIV patients will be committed to a lifetime of therapy to address bone disease and other chronic problems. In the future, newer agents may steer the clinical scenario in unforeseen directions.
在本文中，作者讨论了高效抗逆转录病毒疗法成为常规治疗方式前后风湿综合征的发生情况和流行程度。HIV感染与风湿表现相结合背后的免疫、环境和遗传因素导致了这些疾病的复杂性。文中还讨论了与HIV感染相关的各类病例报告。作者得出结论，随着越来越多的人能够获得更新、更有效的治疗，且死亡率在下降，HIV患者的老年护理即将出现。年轻的HIV患者将需要终身接受治疗以应对骨骼疾病和其他慢性问题。未来，新型药物可能会使临床情况朝着不可预见的方向发展。
