Vega Luis E, Espinoza Luis R
Section of Rheumatology, Air Force Hospital, Aramburú Ave 2nd block, Lima, Peru.
Louisiana State University Health Sciences Center, 433 Bolivar St, New Orleans, LA, 70112, USA.
Clin Rheumatol. 2020 Sep;39(9):2515-2522. doi: 10.1007/s10067-020-05082-8. Epub 2020 Apr 15.
Rheumatic manifestations remain an important clinical manifestation associated to HIV. To date after 4 decades of the onset of the HIV/AIDS pandemic, almost 37 million individuals are living with the infection, including close to 2 million of newly infected individuals. The status, however, of a considerable proportion of HIV/AIDS patients has changed from a near fatal disorder secondary to opportunistic infections to a chronic disease in which renal cardiovascular, diabetes, malignancy, and autoimmune co-morbid disorders have become prevalent and relevant. In addition, the spectrum of rheumatic disorders also has changed since the introduction of HAART and its diagnosis and treatment represents a challenge. The purpose of this review is to define and discuss the HIV-related rheumatic manifestations in the pre- and post-HAART eras.
风湿性表现仍然是与艾滋病毒相关的重要临床表现。自艾滋病毒/艾滋病大流行开始40年来，至今已有近3700万人感染了这种病毒，其中包括近200万新感染个体。然而，相当一部分艾滋病毒/艾滋病患者的状况已从继发于机会性感染的近乎致命的疾病转变为一种慢性疾病，在这种疾病中，肾脏、心血管、糖尿病、恶性肿瘤和自身免疫性合并症已变得普遍且相关。此外，自从引入高效抗逆转录病毒治疗（HAART）以来，风湿性疾病的范围也发生了变化，其诊断和治疗是一项挑战。本综述的目的是界定和讨论HAART时代前后与艾滋病毒相关的风湿性表现。
