Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Eur J Radiol. 2010 Aug;75(2):230-5. doi: 10.1016/j.ejrad.2009.04.061. Epub 2009 May 28.
The purpose of this study was to retrospectively assess possible clinical predictors of malignant pleural effusion in patients with ovarian cancer.
This review was performed on 38 ovarian cancer patients that showed pleural effusion in a CT scan and who underwent thoracocentesis before treatment. CT scans were obtained using a 4-channel multi-detector CT scanner. Fisher's exact test was used to determine the probability of malignant pleural effusion as a function of; amount of ascites, lymph node enlargement, amount of pleural effusion, pleural nodules, and pleural thickening.
Sixteen (42.1%) of the 38 patients had malignant pleural effusion and malignant pleural effusion amounts were greater than those with nonmalignant effusion. Pleural nodules were more frequently found in the malignant pleural effusion group (eight [50%] patients) than in the nonmalignant group (zero [0%] patient) (p<0.001). Supradiaphragmatic lymph node enlargement (with short axis diameter 1cm or more) was more frequent in malignant group (12 [75%] patients) than in the nonmalignant group (two [9.1%] patients) (p<0.001).
The probability of malignant pleural effusion in patients with ovarian cancer was found to be correlated with the amount of pleural effusion, the presence of pleural nodules, and supradiaphragmatic lymph node enlargement.
本研究旨在回顾性评估卵巢癌患者胸腔积液中恶性胸腔积液的可能临床预测因素。
本回顾性研究纳入了 38 例卵巢癌患者，这些患者在 CT 扫描中显示胸腔积液，并在治疗前进行了胸腔穿刺。CT 扫描使用 4 通道多探测器 CT 扫描仪进行。采用 Fisher 确切检验来确定恶性胸腔积液的概率与腹水、淋巴结肿大、胸腔积液量、胸膜结节和胸膜增厚的关系。
38 例患者中 16 例（42.1%）存在恶性胸腔积液，且恶性胸腔积液量大于非恶性胸腔积液量。胸膜结节在恶性胸腔积液组中更为常见（8 例[50%]），而非恶性胸腔积液组中则未见（0 例[0%]）（p<0.001）。膈上淋巴结肿大（短轴直径≥1cm）在恶性组中更为常见（12 例[75%]），而非恶性组中则不常见（2 例[9.1%]）（p<0.001）。
卵巢癌患者恶性胸腔积液的概率与胸腔积液量、胸膜结节和膈上淋巴结肿大有关。
