硫酸镁用于预防脑瘫。

Magnesium sulfate for the prevention of cerebral palsy.

作者信息

Rouse Dwight J

机构信息

Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, AL 35249, USA.

出版信息

Am J Obstet Gynecol. 2009 Jun;200(6):610-2. doi: 10.1016/j.ajog.2009.04.004.

DOI:10.1016/j.ajog.2009.04.004

PMID:19482114

Abstract

Three large, randomized placebo-controlled trials of antenatal magnesium sulfate (MgSO(4)) for fetal neuroprotection have recently been conducted and reported. The results of these trials provide strong support for the utilization of MgSO(4) to lower the risk of cerebral palsy among the survivors of early preterm birth. In the United States, the use of MgSO(4) for fetal neuroprotection has the potential to prevent 1000 cases of handicapping cerebral palsy annually.

摘要

最近进行并报告了三项关于产前使用硫酸镁（MgSO₄）进行胎儿神经保护的大型随机安慰剂对照试验。这些试验结果为使用MgSO₄降低极早早产儿存活者患脑瘫风险提供了有力支持。在美国，使用MgSO₄进行胎儿神经保护每年有可能预防1000例致残性脑瘫病例。