Lands R, Karnad A
Department of Internal Medicine, J.H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614-0002.
South Med J. 1991 Nov;84(11):1405-6. doi: 10.1097/00007611-199111000-00032.
The syndrome of osteolytic lesions and hypercalcemia is commonly associated with well-differentiated B-cell neoplasms, such as multiple myeloma. The association of this syndrome with high-grade non-Hodgkin's lymphoma is rare. We have described a 20-year-old man with a non-T-cell lymphoblastic lymphoma manifested by extensive osteolytic lesions and hypercalcemia (serum calcium value of 13.5 mg/dL), without lymphadenopathy.
溶骨性病变和高钙血症综合征通常与分化良好的B细胞肿瘤相关，如多发性骨髓瘤。该综合征与高级别非霍奇金淋巴瘤的关联较为罕见。我们描述了一名20岁男性，患有非T细胞淋巴母细胞淋巴瘤，表现为广泛的溶骨性病变和高钙血症（血清钙值为13.5mg/dL），无淋巴结病。
