Van de Casteele M, Verhoef G E, Demuynck H, Zacheé P, Boogaerts M A
University Hospital Gasthuisberg, Leuven, Belgium.
Ann Hematol. 1994 Aug;69(2):79-80. doi: 10.1007/BF01698486.
We describe a patient with a long history of typical chronic lymphocytic leukemia (CLL) who developed hypercalcemia, osteolytic bone lesions, and a monoclonal protein, all features of a secretory plasma cell disorder. These features in CLL have been reported in only four previous cases. The hypercalcemia in our patient is felt to result from an increase in the osteoclastic process.
我们描述了一位患有典型慢性淋巴细胞白血病（CLL）病史较长的患者，该患者出现了高钙血症、溶骨性骨病变和单克隆蛋白，这些都是分泌性浆细胞疾病的特征。CLL中的这些特征此前仅在4例病例中报道过。我们患者的高钙血症被认为是破骨细胞过程增加所致。
