He Y X, Hu Y Q, Yu Q F, Tang Z J
Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai.
Southeast Asian J Trop Med Public Health. 1991 Jun;22(2):240-4.
The present paper deals with the susceptibility of common laboratory animals, such as mouse, rat, hamster, jird, rabbit and rhesus monkey, to infection with different isolates of Schistosoma japonicum in the mainland of China under laboratory conditions. With the exception of the rat, all the animals under study were permissive hosts for different isolates though their worm recovery rates varied. The mean body length of pair-worms of the Yunnan isolate was considerably smaller than that of the Anhui, Hubei, Guangxi and Sichuan isolates, and the percentage of male specimens with 7 testes in the Yunnan isolate was also significantly less than that in the other 4 isolates. Judging from the egg index (width/length x 100), the eggs of the Sichuan isolate were broad and short in shape, giving a high index; those of Guangxi and Hubei isolates were oblong, giving the lowest index; the other two isolates from Yunnan and Anhui, lay between these two extremes. The mean prepatent periods were longer in mice, hamsters and rhesus monkeys infected with Yunnan and Guangxi isolates, than those with Sichuan isolate. A dendrogram of the 5 isolates of S. japonicum was constructed on the basis of similarity coefficients by means of fuzzy cluster analysis on the biological characters mentioned above. Our results provide evidence of the existence of different strains of S. japonicum in the mainland of China as shown by comparative studies of their characteristics in the final hosts.
本文研究了小鼠、大鼠、仓鼠、沙鼠、兔和恒河猴等常见实验动物在中国内地实验室条件下对不同日本血吸虫分离株感染的易感性。除大鼠外，所有受试动物都是不同分离株的易感宿主，尽管它们的虫体回收率有所不同。云南分离株的配对虫体平均体长明显小于安徽、湖北、广西和四川分离株，云南分离株中具有7个睾丸的雄虫标本百分比也显著低于其他4个分离株。从虫卵指数（宽/长×100）来看，四川分离株的虫卵宽而短，指数较高；广西和湖北分离株的虫卵呈长方形，指数最低；云南和安徽的另外两个分离株则介于这两个极端之间。感染云南和广西分离株的小鼠、仓鼠和恒河猴的平均潜伏期比感染四川分离株的更长。基于上述生物学特征，通过模糊聚类分析，根据相似系数构建了日本血吸虫5个分离株的聚类图。我们的结果通过对其在终末宿主体内特征的比较研究，证明了中国内地存在不同株的日本血吸虫。
