采用二极管泵浦宽带Cr(3+):LiCAF激光的超高分辨率光学相干断层扫描技术。

Ultrahigh-resolution optical coherence tomography with a diode-pumped broadband Cr(3+):LiCAF laser.

作者信息

Wagenblast Philipp, Ko Tony, Fujimoto James, Kaertner Franz, Morgner Uwe

出版信息

Opt Express. 2004 Jul 12;12(14):3257-63. doi: 10.1364/opex.12.003257.

DOI:10.1364/opex.12.003257

PMID:19483850

Abstract

Ultrahigh resolution optical coherence tomography (OCT) is performed with a broadband, Kerr-lens mode-locked, diode-pumped Cr(3+):LiCAF laser. The laser source has a bandwidth of 89 nm with an output power of 37 mW. OCT imaging is demonstrated with 4.5 microm axial resolution in air or 3.4 microm in tissue. In vivo imaging of the human retina is demonstrated. Ultrahigh resolution OCT images from the Cr(3+):LiCAF laser source were compared with standard resolution images from a commercial OCT system and ultrahigh resolution OCT images from a Kerr-lens modelocked Ti:sapphire laser light source. The Cr(3+):LiCAF source is pumped only by two single-emitter laser diodes, which makes this laser a viable, low-cost alternative to mode-locked Ti:sapphire lasers that are currently used for ultrahigh resolution OCT imaging.

摘要

超高分辨率光学相干断层扫描（OCT）是使用宽带、克尔透镜锁模、二极管泵浦的Cr(3+):LiCAF激光进行的。该激光源带宽为89nm，输出功率为37mW。在空气中轴向分辨率为4.5微米，在组织中为3.4微米时可实现OCT成像。展示了对人视网膜的体内成像。将来自Cr(3+):LiCAF激光源的超高分辨率OCT图像与来自商业OCT系统的标准分辨率图像以及来自克尔透镜锁模钛宝石激光光源的超高分辨率OCT图像进行了比较。Cr(3+):LiCAF光源仅由两个单发射激光二极管泵浦，这使得该激光成为目前用于超高分辨率OCT成像的锁模钛宝石激光的一种可行的低成本替代方案。