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急性弛缓性麻痹:脊髓灰质炎的误诊

Acute flaccid paralysis: a misdiagnosis of poliomyelitis.

作者信息

Nte A R, Frank-Briggs A I

机构信息

Department of Pediatrics, University of Port Harcourt Teaching Hospital, Port Harcourt.

出版信息

Niger J Med. 2009 Jan-Mar;18(1):110-2.

PMID:19485162
Abstract

BACKGROUND

When the goal of eradication of poliomyelitis was set in 1988, the need for active surveillance for acute flaccid paralysis (AFP) became necessary. This has led to the realisation that although the number of polio endemic countries decreased from 125 in 1988 to 6 in 2004, Nigeria is still one of the high transmission areas for the wild virus. The objective of this paper was to review the need for acute flaccid paralysis surveillance by presenting two cases.

METHOD

The case records of two children treated at the University of Port Harcourt Teaching Hospital in 2006 with acute onset of flaccid paralysis were retrieved for presentation.

RESULT

Two girls aged 6 years and 13 years presented with sudden onset of flaccid paralysis for which the clinical diagnoses included poliomyelitis. Their stool specimens taken within 2 weeks of onset of symptoms showed no poliovirus. They initially deteriorated clinically but recovered with little or no residual paralysis.

CONCLUSION

The need to rule out causes other than polio in all acutely paralysed children is hereby highlighted. All polio eradication strategies should continue to be effectively implemented if we must attain the goal of polio eradication.

摘要

背景

1988年设定根除脊髓灰质炎目标时,对急性弛缓性麻痹(AFP)进行主动监测成为必要。这使人们认识到,尽管脊髓灰质炎流行国家的数量从1988年的125个降至2004年的6个,但尼日利亚仍是野生病毒的高传播地区之一。本文的目的是通过介绍两个病例来回顾急性弛缓性麻痹监测的必要性。

方法

检索了2006年在哈科特港大学教学医院治疗的两名急性弛缓性麻痹患儿的病例记录以供展示。

结果

两名年龄分别为6岁和13岁的女孩突然出现弛缓性麻痹,临床诊断包括脊髓灰质炎。她们在症状出现后2周内采集的粪便标本未显示脊髓灰质炎病毒。她们最初临床症状恶化,但恢复后几乎没有或没有残留麻痹。

结论

在此强调了排除所有急性麻痹儿童中脊髓灰质炎以外病因的必要性。如果我们要实现根除脊髓灰质炎的目标,所有根除脊髓灰质炎的策略都应继续有效实施。

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