Ogawa Tetsuya, Ishida Hideki, Matsuda Nami, Fujiu Ayuko, Matsuda Akiko, Ito Kyoko, Ando Yoshitaka, Nitta Kosaku
Department of Medicine, Kidney Center, Tokyo Women's Medical University, Tokyo, Japan.
Hemodial Int. 2009 Jul;13(3):301-6. doi: 10.1111/j.1542-4758.2009.00366.x. Epub 2009 May 27.
Vascular calcification is associated with a poor prognosis in dialysis patients. It can be assessed with computed tomography but simple inoffice techniques may provide useful information. We compared the results obtained with a simple noninvasive technique with those obtained using multidetector computed tomography for aortic arch calcification volume (AoACV) in chronic hemodialysis (HD) patients. The enrolled study subjects were 63 (32 men and 31 women) maintenance HD patients. Calcification of the aortic arch was semiquantitatively estimated with a AoAC score (AoACS) on plain chest radiology. The AoACV was increased, with a mean value of 6.6 ranging from 0% to 36.5%. The coefficient of intraobserver variation was less than 2.5%. Aortic arch calcification score was highly correlated with AoACV (r=0.635, P<0.001). Multiple regression analysis showed age (F value=12.62, P<0.001) and pulse pressure (F value=4.54, P=0.037) to be significant independent determinants of AoACS. In conclusion, a simple measurement of AoACS may be useful for inoffice imaging to choose a therapeutic regimen in HD patients.
血管钙化与透析患者的不良预后相关。它可以通过计算机断层扫描进行评估,但简单的门诊技术可能也能提供有用信息。我们比较了一种简单的非侵入性技术与使用多排计算机断层扫描测量慢性血液透析(HD)患者主动脉弓钙化体积(AoACV)所得到的结果。纳入研究的对象为63名维持性HD患者(32名男性和31名女性)。通过胸部X线平片上的主动脉弓钙化评分(AoACS)对主动脉弓钙化进行半定量评估。AoACV增加,平均值为6.6,范围从0%至36.5%。观察者内变异系数小于2.5%。主动脉弓钙化评分与AoACV高度相关(r = 0.635,P < 0.001)。多元回归分析显示年龄(F值 = 12.62,P < 0.001)和脉压(F值 = 4.54,P = 0.037)是AoACS的显著独立决定因素。总之,简单测量AoACS可能有助于门诊成像,以选择HD患者的治疗方案。