Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Addict Behav. 2009 Sep;34(9):757-63. doi: 10.1016/j.addbeh.2009.05.006. Epub 2009 May 20.
The objective of this study was to identify long-term factors associated with substance use problem among individuals affected by severe mental illness. Prospective data come from the 1994, 1998, and 2000 waves of the Maryland Mental Health Outcomes Survey conducted among a sub-cohort of adult Medicaid recipients affected by serious mental illness. We estimated factors associated with alcohol and drug problem, as well as a hierarchy of substance use problem severity constructed from the alcohol and drug problem outcomes. Drug problem was the strongest factor associated with alcohol problem, and vice versa. Conceptualizing alcohol and drug problem separately, and as a hierarchy of severity, revealed distinct profiles of significant factors. Further research is warranted to explore the utility of modeling substance use problem in terms of a hierarchy of severity.
本研究旨在确定与严重精神疾病患者物质使用问题相关的长期因素。前瞻性数据来自马里兰州心理健康结果调查的 1994 年、1998 年和 2000 年的三次随访,调查对象为受严重精神疾病影响的成年医疗补助受助人亚队列。我们估计了与酒精和药物问题相关的因素,以及从酒精和药物问题结果构建的物质使用问题严重程度层次结构。药物问题是与酒精问题最相关的因素,反之亦然。分别对酒精和药物问题进行概念化,并作为严重程度的层次结构,揭示了具有显著意义的因素的不同特征。需要进一步研究来探索根据严重程度层次结构对物质使用问题进行建模的效用。