Kornev B M, Potapova A V
Ter Arkh. 1991;63(6):134-7.
Variants of renal damage in sarcoidosis demonstrate the diversity of clinical manifestations common to this systemic disease and serve distinctive reference points in the choice of the treatment policy. A well-defined relationship between hypercalciuria associated with sarcoidosis and risk of calcium nephropathy development is, one the one hand, a reliable criterion for the disease activity and, on the other one, the basis for administration of drug the therapy permitting one to control its level (corticosteroids and drugs of the 4-aminoquinoline series). Other variants of renal damage in sarcoidosis, excluding amyloidosis, form the basis for corticosteroid administration even in cases of the presence of renal failure, demonstrating that so-called "dramatic therapy" produces a remarkable beneficial effect characterized by the disappearance of the signs of renal failure.
结节病肾损害的各种表现体现了这种全身性疾病常见临床表现的多样性，并为治疗策略的选择提供了独特的参考依据。一方面，结节病相关的高钙尿症与钙肾病发生风险之间明确的关系是疾病活动的可靠标准，另一方面，也是使用药物治疗以控制其水平（皮质类固醇和4-氨基喹啉系列药物）的依据。结节病肾损害的其他类型，不包括淀粉样变性，即使在存在肾衰竭的情况下也是使用皮质类固醇的依据，这表明所谓的“冲击疗法”能产生显著的有益效果，其特征为肾衰竭体征消失。
