Churin K V, Ianushkene T S, Kuznetsov S R
Ter Arkh. 1991;63(6):96-8.
The investigation was aimed at analyzing membrane-bound calcium in platelets of patients with essential hypertension (EH) and of healthy persons. 55 men were examined. Of these, 38 presented with EH and 17 were healthy. Membrane-bound calcium determined with the help of the chlortetracycline fluorescent probe. The level of membrane-bound calcium in intracellular compartments was higher in patients with EH than in the control. The kinetic curves of the binding of the chlortetracycline fluorescent probe with cellular membranes allow one to reveal disturbances of calcium-dependent membrane processes in persons suffering from EH.
该研究旨在分析原发性高血压（EH）患者和健康人血小板中的膜结合钙。对55名男性进行了检查。其中，38例患有EH，17例健康。借助金霉素荧光探针测定膜结合钙。EH患者细胞内区室的膜结合钙水平高于对照组。金霉素荧光探针与细胞膜结合的动力学曲线使人们能够揭示EH患者钙依赖性膜过程的紊乱。
