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我们从血流动力学不稳定的脑死亡患者身上获取器官的经验。

Our experience with organ procurement from hemodynamically unstable brain dead patients.

作者信息

Naja Zadeh Katayoun, Radpei Badiozzaman, Ghorbani Fariba, Hamidinia Sajjad, Ghobadi Omid, Kardavani Babak, Assari Shervin

机构信息

Organ Procurement Unit, Lung transplantation Research Center, National Research Institute of TB and Lung Disease, Shaheed Beheshti Medical University, Tehran, Iran.

出版信息

Ann Transplant. 2009 Apr-Jun;14(2):20-3.

PMID:19487789
Abstract

BACKGROUND

Effective organ procurement is the result of meticulous care to brain dead patients. Hemodynamic instability may occur in these patients and, if not managed and treated carefully, may lead to loss of precious organs. The aim of the current study is to evaluate the hemodynamic status of brain dead patients and its effect on organ donation.

MATERIAL/METHODS: We retrospectively studied all hospitalization records of brain dead patients at Masih Daneshvari Hospital, Tehran, Iran. We reviewed the patients' status during hospitalization for organ retrieval for their homodynamic condition to see if they had stable or unstable condition. We then followed all cases to see if the hemodynamic condition of the patients had an effect on organ harvest result. For data analysis we used Chi-square test.

RESULTS

In the studied brain dead patients, 95.2% were hemodynamically unstable. Organ procurement was successful in 87.2% of unstable patients. Organ procurement was successful in all patients with stable condition. Unstable hemodynamic condition of the patients had no effect on the rate of successful organ retrieval (p=0.588).

CONCLUSIONS

The majority of brain dead patients in our center were in unstable homodynamic state. Such condition may have no signi fi cant effect on success rate of organ procurement. Proper care for brain dead patients would increase the success rate of organ procurement even in hemodynamically unstable patients.

摘要

背景

有效的器官获取是对脑死亡患者精心护理的结果。这些患者可能会出现血流动力学不稳定的情况,如果处理和治疗不当,可能会导致珍贵器官丧失。本研究的目的是评估脑死亡患者的血流动力学状态及其对器官捐献的影响。

材料/方法:我们回顾性研究了伊朗德黑兰马西赫·达内什瓦里医院所有脑死亡患者的住院记录。我们查看了患者在住院期间进行器官获取时的血流动力学状况,以确定他们的状况是稳定还是不稳定。然后我们跟踪了所有病例,以观察患者的血流动力学状况是否对器官获取结果有影响。对于数据分析,我们使用了卡方检验。

结果

在所研究的脑死亡患者中,95.2%的患者血流动力学不稳定。87.2%的不稳定患者器官获取成功。所有状况稳定的患者器官获取均成功。患者血流动力学不稳定对器官获取成功率没有影响(p = 0.588)。

结论

我们中心的大多数脑死亡患者处于血流动力学不稳定状态。这种状况可能对器官获取成功率没有显著影响。对脑死亡患者进行恰当护理即使在血流动力学不稳定的患者中也会提高器官获取成功率。

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